ENSMUSG00000034459


Mus musculus

Features
Gene ID: ENSMUSG00000034459
  
Biological name :Ifit1
  
Synonyms : Ifit1 / Interferon-induced protein with tetratricopeptide repeats 1 / Q64282
  
Possible biological names infered from orthology : IFIT1B / interferon induced protein with tetratricopeptide repeats 1B / Q5T764
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C1
Gene start: 34640871
Gene end: 34650009
  
Corresponding Affymetrix probe sets: 10462623 (MoGene1.0st)   1450783_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099888
NCBI entrez gene - 15957     See in Manteia.
MGI - MGI:99450
RefSeq - NM_008331
RefSeq Peptide - NP_032357
swissprot - Q64282
Ensembl - ENSMUSG00000034459
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR759879.1ENSDARG00000088069Danio rerio
 ifit10ENSDARG00000007467Danio rerio
 ifit11ENSDARG00000090537Danio rerio
 ifit12ENSDARG00000090977Danio rerio
 ifit14ENSDARG00000071012Danio rerio
 ifit15ENSDARG00000043584Danio rerio
 ifit16ENSDARG00000056976Danio rerio
 ifit8ENSDARG00000057173Danio rerio
 IFIT5ENSGALG00000045085Gallus gallus
 IFIT1BENSG00000204010Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ifit1bl1 / interferon induced protein with tetratricpeptide repeats 1B like 1 / IFIT1B* / Q5T764* / interferon induced protein with tetratricopeptide repeats 1B*ENSMUSG0000007933963
Ifit1bl2 / interferon induced protein with tetratricopeptide repeats 1B like 2 / IFIT1B* / Q5T764* / interferon induced protein with tetratricopeptide repeats 1B*ENSMUSG0000006729760
Ifit2 / Mus musculus interferon-induced protein with tetratricopeptide repeats 2 (Ifit2), transcript variant 2, mRNA. / P09913* / interferon induced protein with tetratricopeptide repeats 2*ENSMUSG0000004593235
Ifit3b / IFIT3* / O14879* / interferon induced protein with tetratricopeptide repeats 3*ENSMUSG0000006248831
Ifit3 / Q64345 / Interferon-induced protein with tetratricopeptide repeats 3 / O14879*ENSMUSG0000007489631


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR027363  Methylthioribose-1-phosphate isomerase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0009615 response to virus IMP
 biological_processGO:0035457 cellular response to interferon-alpha IDA
 biological_processGO:0035458 cellular response to interferon-beta IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002418 increased susceptibility to viral infection "greater likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+,Tg(Alb-E2F1)8Sst/0
Genetic Background: involves: C57BL/6 * CBA

 MP:0009791 increased susceptibility to viral infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a viral invasion or from components of or toxins produced by a virus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+,Tg(Alb-E2F1)8Sst/0
Genetic Background: involves: C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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