ENSMUSG00000034958


Mus musculus

Features
Gene ID: ENSMUSG00000034958
  
Biological name :Atcay
  
Synonyms : Atcay / Caytaxin / Q8BHE3
  
Possible biological names infered from orthology : ATCAY, caytaxin / Q86WG3
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 81204508
Gene end: 81230833
  
Corresponding Affymetrix probe sets: 10371092 (MoGene1.0st)   1434466_at (Mouse Genome 430 2.0 Array)   1434467_at (Mouse Genome 430 2.0 Array)   1454972_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118285
Ensembl peptide - ENSMUSP00000036721
NCBI entrez gene - 16467     See in Manteia.
MGI - MGI:2448730
RefSeq - NM_178662
RefSeq Peptide - NP_848777
swissprot - D6RIJ5
swissprot - Q8BHE3
Ensembl - ENSMUSG00000034958
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atcayaENSDARG00000071678Danio rerio
 atcaybENSDARG00000059781Danio rerio
 ATCAYENSGALG00000001812Gallus gallus
 ATCAYENSG00000167654Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
2 / Prune2 / Q52KR3 / Q8WUY3* / prune homolog 2*ENSMUSG0000003912653
Bnip2 / O54940 / BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 / Q12982* / BCL2 interacting protein 2*ENSMUSG0000001195845
Bnipl / Q99JU7 / Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein / Q7Z465* / BCL2 interacting protein like*ENSMUSG0000002811538
Q5FWK3 / Arhgap1 / Rho GTPase-activating protein 1 / Q07960*ENSMUSG0000002724721
Q9CXP4 / Arhgap8 / Rho GTPase-activating protein 8 / P85298* / PRR5-ARHGAP8* / PRR5-ARHGAP8 readthrough*ENSMUSG0000007895416


Protein motifs (from Interpro)
Interpro ID Name
 IPR001251  CRAL-TRIO lipid binding domain
 IPR022181  Bcl2-/adenovirus E1B 19kDa-interacting protein 2
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0032880 regulation of protein localization IEA
 biological_processGO:0048311 mitochondrion distribution IEA
 biological_processGO:2000212 negative regulation of glutamate metabolic process IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005740 mitochondrial envelope IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031966 mitochondrial membrane IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse ISS
 molecular_functionGO:0019894 kinesin binding IEA
 molecular_functionGO:0050699 WW domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000703 abnormal thymus morphology "anomalous structure or development of the primary lymphoid organ; required for immune system development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55400]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000743 muscle spasms "muscular twitching, cramps and seizures ; frequently associated with calcium deficiency, hypoparathyroidism, vitamin D deficiency or alkalosis " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000938 motor neuron degeneration "retrogressive impairment of function or destruction of the cells that innervate an effector (muscle or glandular) tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Nfiatm1Rmg/Nfiatm1Rmg
Genetic Background: B6.129P2-Nfiatm1Rmg

Allelic Composition: Atcayji-hes2J/Atcayji-hes2J
Genetic Background: BALB/cJ

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Atcayji-hes/Atcayji-hes
Genetic Background: C3H/HeJ-Atcayji-hes

Allelic Composition: Atcayji/Atcayji
Genetic Background: JIGR

Allelic Composition: Atcaym1Btlr/Atcaym1Btlr
Genetic Background: C57BL/6J-Atcaym1Btlr

Allelic Composition: Atcayji-hes/Atcayji-hes,Nxf1Mvb1/Nxf1Mvb1
Genetic Background: involves: C3H/HeJ * C57BL/6

Allelic Composition: Atcayji-hes2J/Atcayji-hes2J
Genetic Background: BALB/cJ

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Atcayji-hes/Atcayji-hes
Genetic Background: C3H/HeJ-Atcayji-hes

Allelic Composition: Atcaym1Btlr/Atcaym1Btlr
Genetic Background: C57BL/6J-Atcaym1Btlr

Allelic Composition: Atcayji-hes2J/Atcayji-hes2J
Genetic Background: BALB/cJ

 MP:0001429 dehydration "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053]
Show

Allelic Composition: Atcayji/Atcayji
Genetic Background: JIGR

 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nfiatm1Rmg/Nfiatm1Rmg
Genetic Background: B6.129P2-Nfiatm1Rmg

Allelic Composition: Atcayji-hes2J/Atcayji-hes2J
Genetic Background: BALB/cJ

 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Atcaym1Btlr/Atcaym1Btlr
Genetic Background: C57BL/6J-Atcaym1Btlr

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Atcayji-hes/Atcayji-hes
Genetic Background: C3H/HeJ-Atcayji-hes

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Atcayji/Atcayji
Genetic Background: JIGR

 MP:0002371 abnormal thymus cortex morphology "anomalous structure or development of the outer area of thymus lobules" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002375 abnormal thymus medulla morphology "anomalous structure or development of the inner area of thymus lobules" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002876 abnormal thyroid physiology "anomalous function of this endocrine gland that normally produces hormones that regulate the metabolic rate of the body " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003313 abnormal locomotor activation "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atcayji-hes/Atcayji-hes,Nxf1Mvb1/Nxf1Mvb1
Genetic Background: involves: C3H/HeJ * C57BL/6

 MP:0003314 dysmetria "an inability to control the range of motion, typified by under- or over-shooting the intended position with the hand, arm, leg or eye" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Atcaym1Btlr/Atcaym1Btlr
Genetic Background: C57BL/6J-Atcaym1Btlr

 MP:0004163 abnormal adenophysis morphology "any malformation or absence of the anterior part of the pituitary that secretes a variety of hormones; its function is regulated by the hypothalamus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004696 abnormal thyroid follicle morphology "any structural abnormality of the small spherical vesicular components of the thyroid gland that are lined with epithelium and contain a colloid substance that both serves as a reservoir of materials for thyroid hormone production and stores thyroid hormones" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Atcayji/Atcayji
Genetic Background: JIGR

 MP:0005323 dystonia "impairment of muscle tone resulting in prolonged muscle contraction and involuntary movements such as repetitive movements, or twisting or writhing of the limbs" [J:84533]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Atcayji-hes/Atcayji-hes
Genetic Background: C3H/HeJ-Atcayji-hes

 MP:0008026 abnormal brain white matter morphology "any structural anomaly of the regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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