ENSMUSG00000035314


Mus musculus

Features
Gene ID: ENSMUSG00000035314
  
Biological name :Gdpd5
  
Synonyms : Gdpd5 / Glycerophosphodiester phosphodiesterase domain-containing protein 5 / Q640M6
  
Possible biological names infered from orthology : glycerophosphodiester phosphodiesterase domain containing 5 / Q8WTR4
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: E1
Gene start: 99381414
Gene end: 99461877
  
Corresponding Affymetrix probe sets: 10555205 (MoGene1.0st)   1424150_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000150361
Ensembl peptide - ENSMUSP00000146372
Ensembl peptide - ENSMUSP00000146887
Ensembl peptide - ENSMUSP00000147184
Ensembl peptide - ENSMUSP00000036175
NCBI entrez gene - 233552     See in Manteia.
MGI - MGI:2686926
RefSeq - XM_017322181
RefSeq - XM_006507635
RefSeq - XM_006507636
RefSeq - XM_006507637
RefSeq - XM_006507639
RefSeq - XM_011241738
RefSeq - NM_201352
RefSeq - XM_006507632
RefSeq - XM_006507633
RefSeq - XM_006507634
RefSeq Peptide - NP_958740
swissprot - A0A1L1STK0
swissprot - A0A140LIN1
swissprot - A0A140LHD5
swissprot - Q640M6
Ensembl - ENSMUSG00000035314
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gdpd5aENSDARG00000077284Danio rerio
 gdpd5bENSDARG00000076962Danio rerio
 GDPD5ENSGALG00000034967Gallus gallus
 GDPD5ENSG00000158555Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gdpd2 / Q9ESM6 / Mus musculus glycerophosphodiester phosphodiesterase domain containing 2 (Gdpd2), transcript variant 3, mRNA. / Q9HCC8* / glycerophosphodiester phosphodiesterase domain containing 2*ENSMUSG0000001935937
Gdpd4 / Q3TT99 / Glycerophosphodiester phosphodiesterase domain-containing protein 4 / Q6W3E5* / glycerophosphodiester phosphodiesterase domain containing 4*ENSMUSG0000003558232


Protein motifs (from Interpro)
Interpro ID Name
 IPR004129  Glycerophosphoryl diester phosphodiesterase
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR030395  Glycerophosphodiester phosphodiesterase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0021522 spinal cord motor neuron differentiation IMP
 biological_processGO:0021895 cerebral cortex neuron differentiation IMP
 biological_processGO:0031175 neuron projection development IMP
 biological_processGO:0045666 positive regulation of neuron differentiation IMP
 biological_processGO:0045746 negative regulation of Notch signaling pathway IDA
 biological_processGO:0045787 positive regulation of cell cycle IMP
 biological_processGO:0048505 regulation of timing of cell differentiation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum IDA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0008889 glycerophosphodiester phosphodiesterase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0047389 glycerophosphocholine phosphodiesterase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
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Allelic Composition: Gbx1tm1b(KOMP)Wtsi/Gbx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Gbx1tm1b(KOMP)Wtsi/H

 MP:0000937 abnormal motor neuron morphology "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Gdpd5tm1.1Itl/Gdpd5tm1.1Itl
Genetic Background: involves: 129 * C57BL/6J

 MP:0000939 reduced motor neuron number "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: Gdpd5tm1Itl/Gdpd5tm1.1Itl,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Gdpd5tm1.1Itl/Gdpd5tm1.1Itl
Genetic Background: involves: 129 * C57BL/6J

Allelic Composition: Gdpd5tm1.1Itl/Gdpd5tm1.1Itl,Tg(Hlxb9-GFP)1Tmj/0
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CBA

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
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Allelic Composition: Gbx1tm1b(KOMP)Wtsi/Gbx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Gbx1tm1b(KOMP)Wtsi/H

 MP:0004948 abnormal neuronal precursor proliferation "any anomaly in the ability of a neuroblast population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gdpd5tm1.1Itl/Gdpd5tm1.1Itl
Genetic Background: involves: 129 * C57BL/6J

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gdpd5tm1Itl/Gdpd5tm1.1Itl,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Gdpd5tm1.1Itl/Gdpd5tm1.1Itl
Genetic Background: involves: 129 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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