ENSMUSG00000035890


Mus musculus

Features
Gene ID: ENSMUSG00000035890
  
Biological name :Rnf126
  
Synonyms : E3 ubiquitin-protein ligase RNF126 / Q91YL2 / Rnf126
  
Possible biological names infered from orthology : Q9BV68 / ring finger protein 126
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 79758515
Gene end: 79766952
  
Corresponding Affymetrix probe sets: 10370632 (MoGene1.0st)   1424514_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039486
NCBI entrez gene - 70294     See in Manteia.
MGI - MGI:1917544
RefSeq - XM_017314081
RefSeq - NM_144528
RefSeq - XM_006514075
RefSeq Peptide - NP_653111
swissprot - Q91YL2
swissprot - Q3U3G2
Ensembl - ENSMUSG00000035890
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf126ENSDARG00000104076Danio rerio
 RNF126ENSGALG00000042948Gallus gallus
 Q9BV68ENSG00000070423Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9D0C1 / Rnf115 / E3 ubiquitin-protein ligase RNF115 / Q9Y4L5* / ring finger protein 115*ENSMUSG0000002809847
Pja2 / Q80U04 / E3 ubiquitin-protein ligase Praja-2 / O43164* / praja ring finger ubiquitin ligase 2*ENSMUSG0000002408326
Pja1 / O55176 / E3 ubiquitin-protein ligase Praja-1 / Q8NG27* / praja ring finger ubiquitin ligase 1*ENSMUSG0000003440322
Q9CY62 / Rnf181 / Mus musculus ring finger protein 181 (Rnf181), transcript variant 11, mRNA. / Q9P0P0* / ring finger protein 181*ENSMUSG0000005585015


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006513 protein monoubiquitination IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IEA
 biological_processGO:0070534 protein K63-linked ubiquitination IDA
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 biological_processGO:0071629 cytoplasm protein quality control by the ubiquitin-proteasome system ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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