ENSMUSG00000034403


Mus musculus

Features
Gene ID: ENSMUSG00000034403
  
Biological name :Pja1
  
Synonyms : E3 ubiquitin-protein ligase Praja-1 / O55176 / Pja1
  
Possible biological names infered from orthology : praja ring finger ubiquitin ligase 1 / Q8NG27
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: C3
Gene start: 99465734
Gene end: 99471273
  
Corresponding Affymetrix probe sets: 10605919 (MoGene1.0st)   1426448_at (Mouse Genome 430 2.0 Array)   1426449_a_at (Mouse Genome 430 2.0 Array)   1451792_a_at (Mouse Genome 430 2.0 Array)   1452083_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109420
Ensembl peptide - ENSMUSP00000109423
Ensembl peptide - ENSMUSP00000109428
Ensembl peptide - ENSMUSP00000132393
Ensembl peptide - ENSMUSP00000109421
NCBI entrez gene - 18744     See in Manteia.
MGI - MGI:1101765
RefSeq - XM_011247546
RefSeq - NM_001083110
RefSeq - NM_001290555
RefSeq - NM_001290556
RefSeq - NM_008853
RefSeq - XM_011247544
RefSeq Peptide - NP_001076579
RefSeq Peptide - NP_001277484
RefSeq Peptide - NP_001277485
RefSeq Peptide - NP_032879
swissprot - B1AXU3
swissprot - O55176
swissprot - Q05CG5
swissprot - B1AXU4
Ensembl - ENSMUSG00000034403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pja2ENSDARG00000100296Danio rerio
 ENSGALG00000000264Gallus gallus
 PJA1ENSG00000181191Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pja2 / Q80U04 / E3 ubiquitin-protein ligase Praja-2 / O43164* / praja ring finger ubiquitin ligase 2*ENSMUSG0000002408346
Q91YL2 / Rnf126 / E3 ubiquitin-protein ligase RNF126 / Q9BV68* / ring finger protein 126*ENSMUSG0000003589012
Q9D0C1 / Rnf115 / E3 ubiquitin-protein ligase RNF115 / Q9Y4L5* / ring finger protein 115*ENSMUSG0000002809810
Q9CY62 / Rnf181 / Mus musculus ring finger protein 181 (Rnf181), transcript variant 11, mRNA. / Q9P0P0* / ring finger protein 181*ENSMUSG000000558507


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR031227  E3 ubiquitin-protein ligase Praja-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030163 protein catabolic process IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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