ENSG00000181191


Homo sapiens

Features
Gene ID: ENSG00000181191
  
Biological name :PJA1
  
Synonyms : PJA1 / praja ring finger ubiquitin ligase 1 / Q8NG27
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q13.1
Gene start: 69160851
Gene end: 69165793
  
Corresponding Affymetrix probe sets: 218667_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467564
Ensembl peptide - ENSP00000363712
Ensembl peptide - ENSP00000467404
Ensembl peptide - ENSP00000355014
Ensembl peptide - ENSP00000363699
Ensembl peptide - ENSP00000363711
NCBI entrez gene - 64219     See in Manteia.
OMIM - 300420
RefSeq - XM_011531011
RefSeq - NM_001032396
RefSeq - NM_022368
RefSeq - NM_145119
RefSeq - XM_005262292
RefSeq Peptide - NP_001027568
RefSeq Peptide - NP_071763
RefSeq Peptide - NP_660095
swissprot - K7EPW5
swissprot - Q8NG27
swissprot - K7EPI8
Ensembl - ENSG00000181191
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pja2ENSDARG00000100296Danio rerio
 ENSGALG00000000264Gallus gallus
 Pja1ENSMUSG00000034403Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PJA2 / O43164 / praja ring finger ubiquitin ligase 2ENSG0000019896149
Q9BV68 / RNF126 / ring finger protein 126ENSG0000007042312
Q9Y4L5 / RNF115 / ring finger protein 115ENSG000002654919
Q9P0P0 / RNF181 / ring finger protein 181ENSG000001688946


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR031227  E3 ubiquitin-protein ligase Praja-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030163 protein catabolic process IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr