ENSG00000168894


Homo sapiens

Features
Gene ID: ENSG00000168894
  
Biological name :RNF181
  
Synonyms : Q9P0P0 / ring finger protein 181 / RNF181
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p11.2
Gene start: 85595725
Gene end: 85597613
  
Corresponding Affymetrix probe sets: 223064_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391326
Ensembl peptide - ENSP00000415246
Ensembl peptide - ENSP00000412025
Ensembl peptide - ENSP00000397109
Ensembl peptide - ENSP00000306906
NCBI entrez gene - 51255     See in Manteia.
OMIM - 612490
RefSeq - NM_016494
RefSeq - XM_005264359
RefSeq Peptide - NP_057578
swissprot - Q9P0P0
swissprot - H7C426
swissprot - C9J1C6
swissprot - F8WBU5
swissprot - C9J391
Ensembl - ENSG00000168894
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7ZW78ENSDARG00000023958Danio rerio
 Q9CY62ENSMUSG00000055850Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y4L5 / RNF115 / ring finger protein 115ENSG0000026549131
Q9BV68 / RNF126 / ring finger protein 126ENSG0000007042329
PJA2 / O43164 / praja ring finger ubiquitin ligase 2ENSG0000019896129
PJA1 / Q8NG27 / praja ring finger ubiquitin ligase 1ENSG0000018119126


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0051865 protein autoubiquitination IDA
 cellular_componentGO:0005737 cytoplasm TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity EXP


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000142867 BCL10 / O95999 / B cell CLL/lymphoma 10  / reaction / complex






 

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