ENSG00000265491


Homo sapiens

Features
Gene ID: ENSG00000265491
  
Biological name :RNF115
  
Synonyms : Q9Y4L5 / ring finger protein 115 / RNF115
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.1
Gene start: 145738868
Gene end: 145824077
  
Corresponding Affymetrix probe sets: 212742_at (Human Genome U133 Plus 2.0 Array)   226468_at (Human Genome U133 Plus 2.0 Array)   239383_at (Human Genome U133 Plus 2.0 Array)   243976_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463650
NCBI entrez gene - 27246     See in Manteia.
RefSeq - NM_014455
RefSeq - XM_005272952
RefSeq Peptide - NP_055270
swissprot - Q9Y4L5
Ensembl - ENSG00000265491
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf115ENSDARG00000062450Danio rerio
 si:ch211-81a5.1ENSDARG00000062900Danio rerio
 Q9D0C1ENSMUSG00000028098Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BV68 / RNF126 / ring finger protein 126ENSG0000007042347
PJA2 / O43164 / praja ring finger ubiquitin ligase 2ENSG0000019896124
PJA1 / Q8NG27 / praja ring finger ubiquitin ligase 1ENSG0000018119120
Q9P0P0 / RNF181 / ring finger protein 181ENSG0000016889415


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IMP
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IMP
 biological_processGO:0051865 protein autoubiquitination IDA
 biological_processGO:0070534 protein K63-linked ubiquitination IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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