ENSG00000198961


Homo sapiens

Features
Gene ID: ENSG00000198961
  
Biological name :PJA2
  
Synonyms : O43164 / PJA2 / praja ring finger ubiquitin ligase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q21.3
Gene start: 109334709
Gene end: 109409994
  
Corresponding Affymetrix probe sets: 201133_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354775
Ensembl peptide - ENSP00000355284
NCBI entrez gene - 9867     See in Manteia.
RefSeq - NM_014819
RefSeq - XM_017010099
RefSeq Peptide - NP_055634
swissprot - O43164
Ensembl - ENSG00000198961
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pja2ENSDARG00000100296Danio rerio
 ENSGALG00000000264Gallus gallus
 Pja2ENSMUSG00000024083Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PJA1 / Q8NG27 / praja ring finger ubiquitin ligase 1ENSG0000018119145
Q9BV68 / RNF126 / ring finger protein 126ENSG0000007042311
Q9Y4L5 / RNF115 / ring finger protein 115ENSG0000026549110
Q9P0P0 / RNF181 / ring finger protein 181ENSG000001688946


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR030639  E3 ubiquitin-protein ligase Praja-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007616 long-term memory ISS
 biological_processGO:0010738 regulation of protein kinase A signaling IMP
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0035329 hippo signaling IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IDA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0034236 protein kinase A catalytic subunit binding IMP
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding IMP
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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