ENSMUSG00000036078


Mus musculus

Features
Gene ID: ENSMUSG00000036078
  
Biological name :Sigmar1
  
Synonyms : O55242 / Sigma non-opioid intracellular receptor 1 / Sigmar1
  
Possible biological names infered from orthology : Q99720
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A5
Gene start: 41738493
Gene end: 41756157
  
Corresponding Affymetrix probe sets: 10512308 (MoGene1.0st)   1416750_at (Mouse Genome 430 2.0 Array)   1440792_x_at (Mouse Genome 430 2.0 Array)   1451956_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056027
Ensembl peptide - ENSMUSP00000071492
NCBI entrez gene - 18391     See in Manteia.
MGI - MGI:1195268
RefSeq - NM_001286541
RefSeq - NM_001286551
RefSeq - NM_001286605
RefSeq - NM_011014
RefSeq - XM_017320027
RefSeq - NM_001286538
RefSeq - NM_001286539
RefSeq - NM_001286540
RefSeq Peptide - NP_001273467
RefSeq Peptide - NP_001273468
RefSeq Peptide - NP_001273469
RefSeq Peptide - NP_001273470
RefSeq Peptide - NP_001273480
RefSeq Peptide - NP_001273534
RefSeq Peptide - NP_035144
swissprot - O55242
swissprot - A2AMS0
Ensembl - ENSMUSG00000036078
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sigmar1ENSDARG00000011418Danio rerio
 Q5ZL84ENSGALG00000028996Gallus gallus
 Q99720ENSG00000147955Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006716  ERG2/sigma1 receptor-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0038003 opioid receptor signaling pathway IEA
 biological_processGO:0043523 regulation of neuron apoptotic process ISO
 biological_processGO:0070207 protein homotrimerization ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005637 nuclear inner membrane IEA
 cellular_componentGO:0005640 nuclear outer membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004985 opioid receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Spi1tm1Kast/Spi1+
Genetic Background: B6.129S2-Spi1tm1Kast

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Slc12a6Gt(OST458419)Lex/Slc12a6Gt(OST458419)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Slc12a6Gt(OST458419)Lex/Slc12a6Gt(OST458419)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0002573 behavioral despair "depression assayed by reduced escape attempts and/or immobility when placed in a stressful situation such as a forced swim test or a suspension test; or failure to seek pleasurable stimuli" [J:80395]
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Allelic Composition: Slc12a6Gt(OST458419)Lex/Slc12a6Gt(OST458419)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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