ENSMUSG00000036381


Mus musculus

Features
Gene ID: ENSMUSG00000036381
  
Biological name :P2ry14
  
Synonyms : P2ry14 / purinergic receptor P2Y, G-protein coupled, 14 / Q9ESG6
  
Possible biological names infered from orthology : purinergic receptor P2Y14 / Q15391
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: D
Gene start: 59113855
Gene end: 59153618
  
Corresponding Affymetrix probe sets: 10498350 (MoGene1.0st)   10498357 (MoGene1.0st)   1424733_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142934
Ensembl peptide - ENSMUSP00000142718
Ensembl peptide - ENSMUSP00000143070
Ensembl peptide - ENSMUSP00000143499
Ensembl peptide - ENSMUSP00000066669
Ensembl peptide - ENSMUSP00000088642
Ensembl peptide - ENSMUSP00000142601
Ensembl peptide - ENSMUSP00000142641
NCBI entrez gene - 140795     See in Manteia.
MGI - MGI:2155705
RefSeq - NM_001287120
RefSeq - NM_001008497
RefSeq - NM_001287119
RefSeq - NM_001287121
RefSeq - NM_001287122
RefSeq - NM_001287123
RefSeq - NM_001287124
RefSeq - NM_133200
RefSeq Peptide - NP_573463
RefSeq Peptide - NP_001274049
RefSeq Peptide - NP_001274050
RefSeq Peptide - NP_001274051
RefSeq Peptide - NP_001274052
RefSeq Peptide - NP_001274053
RefSeq Peptide - NP_001008497
RefSeq Peptide - NP_001274048
swissprot - Q544F4
swissprot - Q9ESG6
swissprot - A0A0G2JGB4
swissprot - A0A0G2JEW9
swissprot - A0A0G2JE58
Ensembl - ENSMUSG00000036381
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RY14ENSDARG00000103305Danio rerio
 P2RY14ENSGALG00000040367Gallus gallus
 P2RY14ENSG00000174944Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gpr87 / Q99MT7 / G-protein coupled receptor 87 / Q9BY21*ENSMUSG0000005143143
P2ry12 / Q9CPV9 / purinergic receptor P2Y, G-protein coupled 12 / Q9H244* / purinergic receptor P2Y12*ENSMUSG0000003635339
P2ry13 / Q9D8I2 / P2Y purinoceptor 13 / Q9BPV8* / purinergic receptor P2Y13*ENSMUSG0000003636237
Gpr171 / Q8BG55 / G protein-coupled receptor 171 / O14626*ENSMUSG0000005007530
Gpr34 / Q9R1K6 / Probable G-protein coupled receptor 34 / Q9UPC5* / G protein-coupled receptor 34*ENSMUSG0000004022927
Gpr82 / Q8BZR0 / Probable G-protein coupled receptor 82 / Q96P67* / G protein-coupled receptor 82*ENSMUSG0000004767822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR005466  P2Y14 purinoceptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0045028 G-protein coupled purinergic nucleotide receptor activity IEA


Pathways (from Reactome)
Pathway description
P2Y receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rbm15tm1.1(MAL)Dgg/Rbm15tm1.1(MAL)Dgg
Genetic Background: B6.129-Rbm15tm1.1(MAL)Dgg

 MP:0002335 decreased airway responsiveness "less easily provoked into bronchoconstriction during bronchial provocation testing" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002626 increased heart rate "greater than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003059 decreased insulin secretion "less than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004875 increased mean arterial blood pressure "increase in the average arterial pressure during a single cardiac cycle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004952 increased spleen weight "greater than average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0006143 increased diastolic blood pressure "abnormal increase in the pressure in the arteries between heart beats when the heart is relaxed" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0006144 increased systolic blood pressure "abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009854 delayed gastric emptying "an increase in the time required for solids or liquids to leave the stomach and enter the intestines" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0010182 decreased susceptibility to weight gain "smaller increase in body weight over time when compared to the average increase in weight on the same diet, with equal energy (calorie) intake" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0010895 increased lung compliance "increased ability of the lung to distend in response to pressure without disruption, usually expressed as the unit volume of change in the lung per unit of pressure" [ISBN:070202788 "Saunders Comprehensive Veterinary Dictionary, 3rd edition"]
Show

Allelic Composition: Fezf2tm1Hibi/Fezf2tm1Hibi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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