ENSMUSG00000036990


Mus musculus

Features
Gene ID: ENSMUSG00000036990
  
Biological name :Otud4
  
Synonyms : B2RRE7 / Otud4 / OTU domain-containing protein 4
  
Possible biological names infered from orthology : OTU deubiquitinase 4 / Q01804
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C1
Gene start: 79639618
Gene end: 79677724
  
Corresponding Affymetrix probe sets: 10573027 (MoGene1.0st)   1431039_at (Mouse Genome 430 2.0 Array)   1434468_at (Mouse Genome 430 2.0 Array)   1434469_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133939
Ensembl peptide - ENSMUSP00000134097
NCBI entrez gene - 73945     See in Manteia.
MGI - MGI:1098801
RefSeq - NM_001256033
RefSeq - NM_001081164
RefSeq - XM_006531406
RefSeq Peptide - NP_001074633
RefSeq Peptide - NP_001242962
swissprot - B2RRE7
swissprot - A0A0R4J260
Ensembl - ENSMUSG00000036990
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 otud4ENSDARG00000077810Danio rerio
 OTUD4ENSGALG00000009968Gallus gallus
 OTUD4ENSG00000164164Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Otud5 / Q3U2S4 / OTU domain-containing protein 5 / Q96G74* / OTU deubiquitinase 5*ENSMUSG000000311547


Protein motifs (from Interpro)
Interpro ID Name
 IPR003323  OTU domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0034122 negative regulation of toll-like receptor signaling pathway IEA
 biological_processGO:0070536 protein K63-linked deubiquitination IDA
 biological_processGO:0071108 protein K48-linked deubiquitination IEA
 biological_processGO:1901537 positive regulation of DNA demethylation IEA
 biological_processGO:1903093 regulation of protein K48-linked deubiquitination IEA
 biological_processGO:2000660 negative regulation of interleukin-1-mediated signaling pathway IDA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0061578 Lys63-specific deubiquitinase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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