ENSMUSG00000037159


Mus musculus

Features
Gene ID: ENSMUSG00000037159
  
Biological name :Wee2
  
Synonyms : Q66JT0 / WEE1 homolog 2 (S. pombe) / Wee2
  
Possible biological names infered from orthology : P0C1S8 / WEE1 homolog 2
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B1
Gene start: 40439088
Gene end: 40466813
  
Corresponding Affymetrix probe sets: 10537480 (MoGene1.0st)   1436751_at (Mouse Genome 430 2.0 Array)   1440774_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122678
Ensembl peptide - ENSMUSP00000144628
Ensembl peptide - ENSMUSP00000038754
NCBI entrez gene - 381759     See in Manteia.
MGI - MGI:3027899
RefSeq - XM_006506326
RefSeq - XM_006506327
RefSeq - NM_201370
RefSeq Peptide - NP_958758
swissprot - Q66JT0
swissprot - D3Z4B4
swissprot - A0A0J9YVE7
Ensembl - ENSMUSG00000037159
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wee2ENSDARG00000012718Danio rerio
 WEE2ENSGALG00000012875Gallus gallus
 WEE2ENSG00000214102Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wee1 / P47810 / WEE 1 homolog 1 (S. pombe) / P30291* / WEE1 G2 checkpoint kinase*ENSMUSG0000003101643
Pkmyt1 / Q9ESG9 / Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase / Q99640* / protein kinase, membrane associated tyrosine/threonine 1*ENSMUSG0000002390819


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017164  Wee1-like protein kinase
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007143 female meiotic nuclear division IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0035038 female pronucleus assembly IMP
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0060631 regulation of meiosis I IMP
 biological_processGO:1900194 negative regulation of oocyte maturation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
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Allelic Composition: Smarcd2tm1.1(KOMP)Vlcg/Smarcd2+
Genetic Background: C57BL/6N-Smarcd2tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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