ENSG00000214102


Homo sapiens

Features
Gene ID: ENSG00000214102
  
Biological name :WEE2
  
Synonyms : P0C1S8 / WEE1 homolog 2 / WEE2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q34
Gene start: 141708353
Gene end: 141731271
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000380675
Ensembl peptide - ENSP00000420388
NCBI entrez gene - 494551     See in Manteia.
OMIM - 614084
RefSeq - NM_001105558
RefSeq Peptide - NP_001099028
swissprot - P0C1S8
swissprot - H7C5P0
Ensembl - ENSG00000214102
  
Related genetic diseases (OMIM): 617996 - Oocyte maturation defect 5, 617996
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wee2ENSDARG00000012718Danio rerio
 WEE2ENSGALG00000012875Gallus gallus
 Wee2ENSMUSG00000037159Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WEE1 / P30291 / WEE1 G2 checkpoint kinaseENSG0000016648345
PKMYT1 / Q99640 / protein kinase, membrane associated tyrosine/threonine 1ENSG0000012756422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017164  Wee1-like protein kinase
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007143 female meiotic nuclear division IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0035038 female pronucleus assembly IEA
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0060631 regulation of meiosis I IEA
 biological_processGO:1900194 negative regulation of oocyte maturation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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