MP:0000599 | enlarged liver | "larger than average size of the liver" [J:65146] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0000607 | abnormal hepatocyte morphology | "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0000691 | enlarged spleen | "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0000877 | abnormal Purkinje cell | "any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0000952 | abnormal CNS glia | "anomalous structure, number or composition of non-neuronal cells of the central nervous system that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0001363 | increased anxiety-related response | "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0002941 | increased circulating alanine transaminase level | "increased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0002981 | increased liver weight | "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0003354 | astrocytosis | "a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0003632 | abnormal nervous system morphology | |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0004756 | abnormal proximal convoluted tubule morphology | "any structural anomaly of the convoluted portion of the duct system of the nephron that extends from the renal glomeurlar capsule in the kidney cortex into the kidney medulla where it joins the loop of Henle; fluid entering the proximal convoluted tubule is reabsorbed into the peritubular capillaries, including approximately two-thirds of the filtered salt and water and all filtered organic solutes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0004952 | increased spleen weight | "greater than average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0005058 | abnormal lysosome morphology | "anomalous structure of any of the cytoplasmic, membrane bound vesicles that contain a variety of hydrolases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0005565 | increased blood urea nitrogen level | "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0005584 | abnormal enzyme/coenzyme activity | "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0006035 | abnormal mitochondrial morphology | "anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0008114 | abnormal Kupffer cell morphology | "any structural anomaly of the phagocytic macrophages residing on the luminal surface of the hepatic sinusoids" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0008918 | microgliosis | "a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0010499 | abnormal ventricle myocardium morphology | "any structural anomaly of the ventricular part of middle layer of the heart, comprised of involuntary muscle" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0010943 | abnormal bronchus epithelium morphology | "any structural anomaly of the epithelial layer of the bronchi" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0011475 | abnormal glycosaminoglycan level | "any change in the amount of glycosaminoglycan, including chondroitin sulfate, dermatan sulfate, keratan sulfate, heparin sulfate, heparin, and/or hyaluronan and other long unbranched polysaccharides consisting of a repeating disaccharide unit" [MGI:csmith] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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MP:0011635 | abnormal mitochondrial crista morphology | "Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061] |
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Allelic Composition: Nbeal2gps/Nbeal2gps Genetic Background: 129S1/SvImJ-Nbeal2gps
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