MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0000160 | kyphosis | "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0000192 | abnormal mineral level | "anomalous concentration of any inorganic substance that has importance in body functions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Nrltm1Asw/Nrltm1Asw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0000198 | hypophosphatemia | "abnormally low concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Nrltm1Asw/Nrltm1Asw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0000297 | abnormal endocardial cushion morphology | "malformation of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds eventually fuse to form the valves between the right and left atrioventricular orifices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0000783 | abnormal forebrain morphology | "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Nrltm1Asw/Nrltm1Asw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0000832 | abnormal thalamus morphology | "malformation or absence of the large ovoid mass of paired bodies containing mostly gray matter and forming part of the lateral wall of the third ventricle of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Nrltm1Asw/Nrltm1Asw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001015 | small superior cervical ganglion | "reduced size of the group of neurons that is the largest of the ganglia of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [J:23882] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0001303 | abnormal lens morphology | "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
Allelic Composition: Slc20a2tm1b(EUCOMM)Wtsi/Slc20a2+ Genetic Background: C57BL/6N-Slc20a2tm1b(EUCOMM)Wtsi/Ieg
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MP:0001304 | cataracts | "complete or partial opacity of the lens" [J:65031] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0001322 | abnormal iris morphology | "structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0002968 | increased circulating alkaline phosphatase level | "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0003795 | abnormal bone structure | |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0003869 | ectopic cartilage | "positional abnormality of cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0003961 | decreased lean body mass | "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0004174 | abnormal spine curvature | "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0004613 | fusion of vertebral arches | "improper union of the dorsal part of adjacent vertebra" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0005176 | eyelids fail to open | "eyes remain shut throughout life" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0005293 | impaired glucose tolerance | "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Slc20a2tm1b(EUCOMM)Wtsi/Slc20a2+ Genetic Background: C57BL/6N-Slc20a2tm1b(EUCOMM)Wtsi/Ieg
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MP:0006007 | abnormal basal ganglion morphology | "malformation or absence of any of a group of nuclei associated with the ability to carry out willed movements, including the caudate, putamen, nucleus accumbens, globus pallidus, substantia nigra, and subthalamic nucleus" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Nrltm1Asw/Nrltm1Asw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0006062 | abnormal vena cava morphology | "structural malformation of either of the two largest veins in the body " [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0006093 | arteriovenous malformation | "fusion of an artery and vein without an intervening capillary bed" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93125] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0006358 | absent pinna reflex | "complete failure to respond to an auditory stimulus by a characteristic ear twitch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0008918 | microgliosis | "a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nrltm1Asw/Nrltm1Asw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009820 | abnormal liver vasculature morphology | "any structural anomaly of the blood vessel network of the bile-secreting exocrine gland" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0010052 | increased grip strength | "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+ Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi
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MP:0010092 | increased circulating magnesium level | "an elevation in the blood concentration of magnesium" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0010096 | abnormal incisor color | "anomaly in the color and shading of the incisor, which normally presents in shades of white" [PMID:12407097] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0010124 | decreased bone mineral content | "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0010440 | anomalous pulmonary venous connection | "abnormal development and attachment of the four pulmonary veins that normally attach to the left atrium of the heart, resulting in either partial or complete anomalous drainage back into the systemic venous circulation via an anomalous connection to the right atrium, the superior or inferior vena cava, the innominate vein, the coronary sinus or the left subclavian artery" [http://emedicine.medscape.com] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Slc20a2tm1b(EUCOMM)Wtsi/Slc20a2+ Genetic Background: C57BL/6N-Slc20a2tm1b(EUCOMM)Wtsi/Ieg
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MP:0013278 | decreased fasted circulating glucose level | "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0013836 | abnormal hypoglossal nerve topology | "abnormal position of the hypoglossal nerve " [MGI:csmith] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0013847 | retropleural edema | "accumulation of watery or serous fluid in the retropleural space" [MGI:csmith] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0013848 | subcutaneous edema | "accumulation of watery or serous fluid in the subcutaneous region below the skin" [MGI:csmith] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0013968 | multiple persisting craniopharyngeal ducts | |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0014018 | embryo tumor | "presence of an unspecified tumor or aberrant growth in a prenatal orgnaism" [MGI:csmith] |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0014019 | embryo cyst | |
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Allelic Composition: Ush1ctm1a(KOMP)Wtsi/Ush1ctm1a(KOMP)Wtsi Genetic Background: C57BL/6N-Ush1ctm1a(KOMP)Wtsi/Wtsi
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MP:0030014 | calcified brain | "pathologic deposition of calcium salts in the brain" [] {comment="MGI:anna"} |
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Allelic Composition: Nrltm1Asw/Nrltm1Asw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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