Manteia

ENSMUSG00000037894

Mus musculus

Features

Gene ID:	ENSMUSG00000037894

Biological name :	H2afz

Synonyms :	H2afz / Histone H2A.Z / P0C0S6

Possible biological names infered from orthology :	H2A histone family member Z / P0C0S5

Species:	Mus musculus

Chr. number:	3
Strand:	1
Band:	G3
Gene start:	137864487
Gene end:	137866922

Corresponding Affymetrix probe sets:	10496379 (MoGene1.0st) 10540999 (MoGene1.0st) 1416415_a_at (Mouse Genome 430 2.0 Array) 1438091_a_at (Mouse Genome 430 2.0 Array) 1438092_x_at (Mouse Genome 430 2.0 Array) 1456032_x_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000036907 Ensembl peptide - ENSMUSP00000133339 Ensembl peptide - ENSMUSP00000133541 Ensembl peptide - ENSMUSP00000134059 NCBI entrez gene - 51788 See in Manteia. MGI - MGI:1888388 RefSeq - NM_001316995 RefSeq - NM_016750 RefSeq Peptide - NP_001303924 RefSeq Peptide - NP_058030 swissprot - Q3UA95 swissprot - G3UWL7 swissprot - P0C0S6 swissprot - G3UX40 Ensembl - ENSMUSG00000037894

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
H2afv / Q3THW5 / Histone H2A.V / Q71UI9* / H2A histone family member V*	ENSMUSG00000041126	98

Protein motifs (from Interpro)

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006342	chromatin silencing	IBA
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0071392	cellular response to estradiol stimulus	IEA
cellular_component	GO:0000786	nucleosome	IEA
cellular_component	GO:0000790	nuclear chromatin	IBA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005694	chromosome	IEA
cellular_component	GO:0005719	nuclear euchromatin	IEA
cellular_component	GO:0005720	nuclear heterochromatin	IEA
molecular_function	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	IEA
molecular_function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	IEA
molecular_function	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	IEA
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0031490	chromatin DNA binding	IEA
molecular_function	GO:0031492	nucleosomal DNA binding	IEA
molecular_function	GO:0046982	protein heterodimerization activity	IEA

Pathways (from Reactome)

Pathway description

Packaging Of Telomere Ends

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002718	abnormal inner cell mass	"malformed or absent cells of the blastocyst that develop into the body of the embryo" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Col1a1^tm1.1Jcm/Col1a1⁺ Genetic Background: either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)
MP:0011096	complete embryonic lethality before somite formation	"death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]	Show Allelic Composition: Col1a1^tm1.1Jcm/Col1a1⁺ Genetic Background: either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr