ENSMUSG00000037949


Mus musculus

Features
Gene ID: ENSMUSG00000037949
  
Biological name :Ano10
  
Synonyms : Ano10 / Anoctamin-10 / Q8BH79
  
Possible biological names infered from orthology : Q9NW15
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F4
Gene start: 122175874
Gene end: 122294423
  
Corresponding Affymetrix probe sets: 10597883 (MoGene1.0st)   1426672_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000149488
Ensembl peptide - ENSMUSP00000151189
Ensembl peptide - ENSMUSP00000151030
Ensembl peptide - ENSMUSP00000150161
Ensembl peptide - ENSMUSP00000149772
Ensembl peptide - ENSMUSP00000045214
Ensembl peptide - ENSMUSP00000149278
NCBI entrez gene - 102566     See in Manteia.
MGI - MGI:2143103
RefSeq - XM_017313064
RefSeq - NM_001271873
RefSeq - NM_133979
RefSeq - XM_011242928
RefSeq - XM_011242929
RefSeq Peptide - NP_001258802
RefSeq Peptide - NP_598740
swissprot - A0A1L1SR14
swissprot - A0A1L1SS60
swissprot - Q8BH79
swissprot - A0A1L1SRJ0
swissprot - A0A1L1SV36
Ensembl - ENSMUSG00000037949
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ano10aENSDARG00000057736Danio rerio
 ANO10ENSGALG00000042371Gallus gallus
 ANO10ENSG00000160746Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ano8 / Q6PB70 / Anoctamin-8 / Q9HCE9*ENSMUSG0000003486335
Ano7 / Q14AT5 / Anoctamin-7 / Q6IWH7*ENSMUSG0000003410726
Ano4 / Q8C5H1 / Anoctamin-4 / Q32M45*ENSMUSG0000003518925
Ano6 / Q6P9J9 / Anoctamin-6 / Q4KMQ2*ENSMUSG0000006421025
Ano5 / Q75UR0 / Anoctamin-5 / Q75V66*ENSMUSG0000005548925
Ano3 / A2AHL1 / Anoctamin-3 / Q9BYT9*ENSMUSG0000007496824
Ano2 / Q8CFW1 / Anoctamin-2 / Q9NQ90*ENSMUSG0000003811523
Ano1 / Q8BHY3 / Anoctamin-1 / Q5XXA6*ENSMUSG0000003107522
Ano9 / P86044 / Anoctamin-9 / A1A5B4*ENSMUSG0000005466220


Protein motifs (from Interpro)
Interpro ID Name
 IPR007632  Anoctamin
 IPR031291  Anoctamin-10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006812 cation transport ISO
 biological_processGO:0006821 chloride transport ISO
 biological_processGO:0034220 ion transmembrane transport IEA
 cellular_componentGO:0005622 intracellular ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005227 calcium activated cation channel activity ISO
 molecular_functionGO:0005229 intracellular calcium activated chloride channel activity IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005343 increased circulating aspartate transaminase level "greater than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptentm1Rdp/Ptentm1Rdp,Tg(tetO-BRAF*V600E)29Lc/0,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129/Sv * C57BL/6J * FVB * SJL

 MP:0008210 increased mature B cell number "greater number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptentm1Rdp/Ptentm1Rdp,Tg(tetO-BRAF*V600E)29Lc/0,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129/Sv * C57BL/6J * FVB * SJL

 MP:0010090 increased circulating creatine kinase level "an elevation in the concentration in the blood of an enzyme that catalyzes the reversible transfer of creatine to phosphocreatine" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptentm1Rdp/Ptentm1Rdp,Tg(tetO-BRAF*V600E)29Lc/0,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129/Sv * C57BL/6J * FVB * SJL

 MP:0014208 decreased intestinal epithelial chloride transmembrane transport 
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Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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