ENSMUSG00000038467


Mus musculus

Features
Gene ID: ENSMUSG00000038467
  
Biological name :Chmp4b
  
Synonyms : Charged multivesicular body protein 4b / Chmp4b / Q9D8B3
  
Possible biological names infered from orthology : Q9H444
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 154651705
Gene end: 154694785
  
Corresponding Affymetrix probe sets: 10477572 (MoGene1.0st)   1426240_at (Mouse Genome 430 2.0 Array)   1451988_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000036206
NCBI entrez gene - 75608     See in Manteia.
MGI - MGI:1922858
RefSeq - NM_029362
RefSeq Peptide - NP_083638
swissprot - Q9D8B3
Ensembl - ENSMUSG00000038467
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chmp4baENSDARG00000016255Danio rerio
 Q6IQ73ENSDARG00000007323Danio rerio
 CHMP4BENSGALG00000002095Gallus gallus
 CHMP4BENSG00000101421Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chmp4c / Q9D7F7 / Charged multivesicular body protein 4c / Q96CF2*ENSMUSG0000002753662


Protein motifs (from Interpro)
Interpro ID Name
 IPR005024  Snf7 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IEA
 biological_processGO:0000920 cell separation after cytokinesis IEA
 biological_processGO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006997 nucleus organization IEA
 biological_processGO:0007034 vacuolar transport IEA
 biological_processGO:0007080 mitotic metaphase plate congression IEA
 biological_processGO:0010458 exit from mitosis IEA
 biological_processGO:0010506 regulation of autophagy IMP
 biological_processGO:0010824 regulation of centrosome duplication IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031468 nuclear envelope reassembly IEA
 biological_processGO:0036438 maintenance of lens transparency IEA
 biological_processGO:0039702 viral budding via host ESCRT complex IEA
 biological_processGO:0046755 viral budding IEA
 biological_processGO:0050792 regulation of viral process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0090148 membrane fission IEA
 biological_processGO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway IEA
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:1901673 regulation of mitotic spindle assembly IEA
 biological_processGO:1902188 positive regulation of viral release from host cell IEA
 biological_processGO:1902902 negative regulation of autophagosome assembly IEA
 cellular_componentGO:0000815 ESCRT III complex IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005635 nuclear envelope ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030496 midbody ISO
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0031982 vesicle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
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Allelic Composition: Pbx1tm1Mlc/Pbx1tm3.1Mlc,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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