ENSMUSG00000038552


Mus musculus

Features
Gene ID: ENSMUSG00000038552
  
Biological name :Fndc4
  
Synonyms : Fndc4 / Mus musculus fibronectin type III domain containing 4 (Fndc4), transcript variant 1, mRNA. / Q3TR08
  
Possible biological names infered from orthology : fibronectin type III domain containing 4 / Q9H6D8
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: B1
Gene start: 31292242
Gene end: 31296080
  
Corresponding Affymetrix probe sets: 10529206 (MoGene1.0st)   1431226_a_at (Mouse Genome 430 2.0 Array)   1449012_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047185
Ensembl peptide - ENSMUSP00000144229
Ensembl peptide - ENSMUSP00000144195
Ensembl peptide - ENSMUSP00000144142
Ensembl peptide - ENSMUSP00000127404
NCBI entrez gene - 64339     See in Manteia.
MGI - MGI:1917195
RefSeq - XM_011240762
RefSeq - NM_001356945
RefSeq - NM_022424
RefSeq - XM_006504044
RefSeq Peptide - NP_001343874
RefSeq Peptide - NP_001343875
RefSeq Peptide - NP_071869
swissprot - A0A0J9YUE6
swissprot - Q3TR08
swissprot - A0A0J9YUK8
swissprot - B9EI95
swissprot - A0A0J9YUI2
Ensembl - ENSMUSG00000038552
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fndc4aENSDARG00000043396Danio rerio
 fndc4bENSDARG00000009949Danio rerio
 FNDC4ENSGALG00000016507Gallus gallus
 FNDC4ENSG00000115226Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fndc5 / Q8K4Z2 / Fibronectin type III domain-containing protein 5 Irisin / Q8NAU1* / fibronectin type III domain containing 5*ENSMUSG0000000133442


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0050728 negative regulation of inflammatory response IDA
 biological_processGO:0071559 response to transforming growth factor beta IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
Show

Allelic Composition: Plac8tm1Bhk/Plac8+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0008537 increased susceptibility to induced colitis "increased severity or induction threshold of colitis upon treatment of an organism with intestinal inflammation agents such as dextran sodium sulfate (DSS)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Plac8tm1Bhk/Plac8+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0013956 decreased colon length "reduced length of the portion of the large intestine between the cecum and the rectum" [ISBN:0683400088]
Show

Allelic Composition: Plac8tm1Bhk/Plac8+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr