ENSMUSG00000039470


Mus musculus

Features
Gene ID: ENSMUSG00000039470
  
Biological name :Zdhhc2
  
Synonyms : P59267 / Zdhhc2 / zinc finger, DHHC domain containing 2
  
Possible biological names infered from orthology : Q9UIJ5 / zinc finger DHHC-type containing 2
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A4
Gene start: 40423815
Gene end: 40510268
  
Corresponding Affymetrix probe sets: 10571399 (MoGene1.0st)   1452654_at (Mouse Genome 430 2.0 Array)   1452655_at (Mouse Genome 430 2.0 Array)   1452656_at (Mouse Genome 430 2.0 Array)   1453481_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041727
Ensembl peptide - ENSMUSP00000123070
Ensembl peptide - ENSMUSP00000129996
NCBI entrez gene - 70546     See in Manteia.
MGI - MGI:1923452
RefSeq - XM_006509487
RefSeq - NM_001357249
RefSeq - NM_178395
RefSeq - XM_006509485
RefSeq Peptide - NP_001344178
RefSeq Peptide - NP_848482
swissprot - P59267
Ensembl - ENSMUSG00000039470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zdhhc2ENSDARG00000034757Danio rerio
 ENSGALG00000034554Gallus gallus
 ENSGALG00000013655Gallus gallus
 Q9UIJ5ENSG00000104219Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5Y5T1 / Zdhhc20 / zinc finger, DHHC domain containing 20 / Q5W0Z9* / zinc finger DHHC-type containing 20*ENSMUSG0000002196960
Q8BGJ0 / Zdhhc15 / zinc finger, DHHC domain containing 15 / Q96MV8* / zinc finger DHHC-type containing 15*ENSMUSG0000003390652
Q8R173 / Zdhhc3 / zinc finger, DHHC domain containing 3 / Q9NYG2* / zinc finger DHHC-type containing 3*ENSMUSG0000002578621
Q91WU6 / Zdhhc7 / zinc finger, DHHC domain containing 7 / Q9NXF8* / zinc finger DHHC-type containing 7*ENSMUSG0000003182320
Q5Y5T3 / Zdhhc23 / zinc finger, DHHC domain containing 23 / Q8IYP9* / zinc finger DHHC-type containing 23*ENSMUSG0000003630417
Zdhhc25 / zinc finger, DHHC domain containing 25ENSMUSG0000005411715
Q9D270 / Zdhhc21 / zinc finger, DHHC domain containing 21 / Q8IVQ6* / zinc finger DHHC-type containing 21*ENSMUSG0000002840315


Protein motifs (from Interpro)
Interpro ID Name
 IPR001594  Palmitoyltransferase, DHHC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018345 protein palmitoylation ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0055038 recycling endosome membrane IDA
 molecular_functionGO:0016409 palmitoyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0019706 protein-cysteine S-palmitoyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Surfactant metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002753 dilated left ventricle "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0003769 abnormal lip morphology "anomalous structure or development of the fleshy margins of the mouth" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000046841 Ckap4 / Q8BMK4 / Cytoskeleton-associated protein 4 / Q07065*  / reaction






 

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