ENSMUSG00000039536


Mus musculus

Features
Gene ID: ENSMUSG00000039536
  
Biological name :Stau1
  
Synonyms : Q9Z108 / Stau1 / staufen double-stranded RNA binding protein 1
  
Possible biological names infered from orthology : O95793
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 166947549
Gene end: 166996299
  
Corresponding Affymetrix probe sets: 10489831 (MoGene1.0st)   1422766_at (Mouse Genome 430 2.0 Array)   1435347_at (Mouse Genome 430 2.0 Array)   1450741_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042626
Ensembl peptide - ENSMUSP00000104859
Ensembl peptide - ENSMUSP00000104861
Ensembl peptide - ENSMUSP00000139039
Ensembl peptide - ENSMUSP00000104858
NCBI entrez gene - 20853     See in Manteia.
MGI - MGI:1338864
RefSeq - XM_011239406
RefSeq - NM_001109905
RefSeq - NM_001109906
RefSeq - NM_001291160
RefSeq - NM_011490
RefSeq - XM_006499071
RefSeq - XM_006499072
RefSeq Peptide - NP_001103376
RefSeq Peptide - NP_001278089
RefSeq Peptide - NP_035620
RefSeq Peptide - NP_001103375
swissprot - Q9DBE7
swissprot - Q9Z108
swissprot - V9GX87
swissprot - A2A5R8
swissprot - A2A5S3
Ensembl - ENSMUSG00000039536
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stau1ENSDARG00000044182Danio rerio
 STAU1ENSGALG00000004736Gallus gallus
 STAU1ENSG00000124214Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Stau2 / Q8CJ67 / staufen double-stranded RNA binding protein 2 / Q9NUL3*ENSMUSG0000002592041


Protein motifs (from Interpro)
Interpro ID Name
 IPR014720  Double-stranded RNA-binding domain
 IPR032478  Staufen, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008298 intracellular mRNA localization IDA
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0045070 positive regulation of viral genome replication ISO
 biological_processGO:0046726 positive regulation by virus of viral protein levels in host cell ISO
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005791 rough endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0010494 cytoplasmic stress granule IDA
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule ISO
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0044297 cell body ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008157 protein phosphatase 1 binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: B6.129S7-Trp53tm1Ldo

 MP:0004998 decreased CNS synapse formation "a reduction in the frequency of the process of generating the initial connections between an axon and effector tissue or neuron" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: B6.129S7-Trp53tm1Ldo

 MP:0008143 abnormal dendrite morphology "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: B6.129S7-Trp53tm1Ldo

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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