Manteia - Molecule gene

ENSMUSG00000040040

Mus musculus

Features

Gene ID:	ENSMUSG00000040040

Biological name :	Ift88

Synonyms :	Ift88 / intraflagellar transport 88

Possible biological names infered from orthology :	Q13099

Species:	Mus musculus

Chr. number:	14
Strand:	1
Band:	C3
Gene start:	57424062
Gene end:	57517936

Corresponding Affymetrix probe sets:	10415608 (MoGene1.0st) 1448652_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000130475 Ensembl peptide - ENSMUSP00000113768 Ensembl peptide - ENSMUSP00000120286 NCBI entrez gene - 21821 See in Manteia. MGI - MGI:98715 RefSeq - XM_006518810 RefSeq - XM_011245008 RefSeq - XM_011245007 RefSeq - NM_009376 RefSeq - XM_006518811 RefSeq Peptide - NP_033402 swissprot - F6QZ23 swissprot - D6RJ41 swissprot - G3X9Z7 Ensembl - ENSMUSG00000040040

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ift88	ENSDARG00000027234	Danio rerio
	ENSGALG00000017134	Gallus gallus
	ENSGALG00000043412	Gallus gallus
IFT88	ENSG00000032742	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

ID

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR011990	Tetratricopeptide-like helical domain superfamily
IPR013026	Tetratricopeptide repeat-containing domain
IPR019734	Tetratricopeptide repeat

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
cellular_component	GO:0005814	centriole	IEA
cellular_component	GO:0005929	cilium	IEA
cellular_component	GO:0031514	motile cilium	IEA
cellular_component	GO:0036064	ciliary basal body	IEA
molecular_function	GO:0005515	protein binding	IEA

Pathways (from Reactome)

Pathway description

Hedgehog off state

Intraflagellar transport

Hedgehog on state

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000026	abnormal inner ear morphology	"malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]	Show Allelic Composition: Adgrv1^tm1Pwh/Adgrv1^tm1Pwh Genetic Background: involves: 129S1/Sv * C57BL/6J
MP:0000111	cleft palate	"congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Ror1^tm1.2Meg/Ror1^tm1.2Meg,Ror2^tm1.2Meg/Ror2^tm1.2Meg Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
MP:0000166	abnormal chondrocyte morphology	"anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Ift88^tm1Rpw/Ift88^tm1.1Bky Genetic Background: involves: 129 * 129P2/OlaHsd
MP:0000292	distended pericardial sacs	"stretched outer parietal layer of the pericardium" [J:25248]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Ift88^tm1Rpw/Ift88^tm1.1Bky Genetic Background: involves: 129 * 129P2/OlaHsd
MP:0000547	short limbs	"reduced average length of the extremities" [MGI:CLS, J:61509]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
MP:0000554	abnormal carpal bone morphology	"malformation of the nine nodular bones of the joint between the forelimb bones and the front paws consisting of the scapholunar, triangular, greater multiangular, lesser multiangular, capitate, hamate, centrale and the sesamoids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]	Show Allelic Composition: Adgrv1^tm1Pwh/Adgrv1^tm1Pwh Genetic Background: involves: 129S1/Sv * C57BL/6J
MP:0000562	polydactyly	"greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Scn8a^nur14/Scn8a^nur14 Genetic Background: involves: C57BL/6J Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: C3.B6J-Ift88^fxo Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: 129/Sv * FVB/N Allelic Composition: Ift88^tm1Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0000598	abnormal liver morphology	"malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv * FVB/N
MP:0000783	abnormal forebrain morphology	"malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0000787	abnormal telencephalon morphology	"any malformation or absence of the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs Allelic Composition: Ift88^cbbs/Ift88^tm1.1Bky Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
MP:0000830	abnormal diencephalon morphology	"any malformation or absence of the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: involves: C3HeB/FeJ * C57BL/6J
MP:0000897	abnormal midbrain	"malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: C3.B6J-Ift88^fxo
MP:0000898	midbrain hyperplasia	"increased cell number associated with the middle of the three cerebral vesicles of the embryo" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:49840]	Show Allelic Composition: Ift88^cbbs/Ift88^tm1.1Bky Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
MP:0000914	exencephaly	"neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs Allelic Composition: Bbs7^tm1Vcs/Bbs7^tm1Vcs,Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0000925	abnormal floor plate morphology	"malformation or absence of a transient group of neuroepithelial cells located at the ventral midline of the neural tube that profoundly influences the development of the vertebrate central nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: involves: C3HeB/FeJ * C57BL/6J Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: C3.B6J-Ift88^fxo
MP:0000926	absent floor plate	"missing ventral midline thinning of the developing neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35802]	Show Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: involves: C3HeB/FeJ * C57BL/6J
MP:0000929	open neural tube	"incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Msx2-cre)5Rem/? Genetic Background: involves: 129P2/OlaHsd
MP:0000930	wavy neural tube	"undulations in the embryonic neural tube" [J:37888]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0001176	abnormal lung development	"malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]	Show Allelic Composition: Pou3f1^tm1Mejr/Pou3f1^tm1Mejr Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001178	pulmonary hypoplasia	"reduced size of the respiratory organ due to incomplete development of all or part of the organ " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Ift88^tm1Rpw/Ift88^tm1.1Bky Genetic Background: involves: 129 * 129P2/OlaHsd
MP:0001293	anophthalmia	"congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]	Show Allelic Composition: Ror1^tm1.2Meg/Ror1^tm1.2Meg,Ror2^tm1.2Meg/Ror2^tm1.2Meg Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: Golga3^{tm1b(EUCOMM)Hmgu}/Golga3^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Golga3^{tm1b(EUCOMM)Hmgu}/H
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: Golga3^{tm1b(EUCOMM)Hmgu}/Golga3^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Golga3^{tm1b(EUCOMM)Hmgu}/H
MP:0001511	disheveled coat	"coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0001697	abnormal embryo size	"anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Htr1b^{tm1.1(KOMP)Vlcg}/Htr1b⁺ Genetic Background: C57BL/6N-Htr1b^{tm1.1(KOMP)Vlcg}/J Allelic Composition: Ift88^{tm1.1(KOMP)Vlcg}/Ift88⁺ Genetic Background: C57BL/6N-Ift88^{tm1.1(KOMP)Vlcg}/J
MP:0001700	abnormal embryo turning	"atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Htr1b^{tm1.1(KOMP)Vlcg}/Htr1b⁺ Genetic Background: C57BL/6N-Htr1b^{tm1.1(KOMP)Vlcg}/J Allelic Composition: Ift88^{tm1.1(KOMP)Vlcg}/Ift88⁺ Genetic Background: C57BL/6N-Ift88^{tm1.1(KOMP)Vlcg}/J
MP:0001706	abnormal left-right axis patterning	"anomaly in the formation or development of the body or a specific organ of the body in relation to the left and right sides of the body or organ" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: involves: C3HeB/FeJ * C57BL/6J
MP:0001730	embryonic growth arrest	"the cessation of development beyond a particular stage" [J:17509]	Show Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: involves: C3HeB/FeJ * C57BL/6J
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0001787	pericardial edema	"accumulation of watery fluid in the pericardial sac of the heart" [J:52597]	Show Allelic Composition: Ror1^tm1.2Meg/Ror1^tm1.2Meg,Ror2^tm1.2Meg/Ror2^tm1.2Meg Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
MP:0001944	abnormal pancreas morphology	"malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu , Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: C3H * FVB/N
MP:0002113	abnormal skeleton development	"anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^tm1Rpw/Ift88^tm1.1Bky Genetic Background: involves: 129 * 129P2/OlaHsd
MP:0002151	abnormal neural tube morphology/development	"anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Msx2-cre)5Rem/? Genetic Background: involves: 129P2/OlaHsd
MP:0002427	dwarfism	"abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Jarid2^Gt(ROSA)1Gel/Jarid2^Gt(ROSA)1Gel Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002633	persistent truncus arteriosis	"complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0002693	abnormal pancreas physiology	"abberrant function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0002694	abnormal pancreas secretion	"altered ability of the pancreas to release its products" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0002884	abnormal branchial arches	"malformation or anomaly in the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0002896	abnormal bone mineralization	"defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
MP:0002925	abnormal cardiovascular development	"aberrant formation or incomplete differentiation of the cardiovascular system" [RGD:Rat Genome Database submission]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0002928	abnormal bile duct morphology	"malformation of the channels that secrete bile from the liver to the gall bladder and intestines" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: 129/Sv * FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv * FVB/N
MP:0002968	increased circulating alkaline phosphatase level	"elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw
MP:0002988	decreased urine osmolarity	"reduction in the concentration of ions in the urine compared to normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:83000]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw
MP:0003055	abnormal epiphyseal plate morphology	"malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Jarid2^Gt(ROSA)1Gel/Jarid2^Gt(ROSA)1Gel Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0003068	enlarged kidney	"larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0003232	abnormal forebrain development	"anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0003333	liver fibrosis	"invasion of fibrous connective tissue into the liver, often resulting from inflammation or injury " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw
MP:0003336	pancreatic cysts	"the appearance of fluid-filled sacs within the pancreas" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0003400	kinked neural tube	"twists or kinks in the embryonic neural tube" [J:66514, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0003675	kidney cysts	"abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: C3H * FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: 129/Sv * FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv * FVB/N
MP:0003723	abnormal long bone morphology	"malformation of any of the several elongated bones of the extremities " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0003840	abnormal coronal suture morphology	"malformation of the articulation between the parietal bones and the frontal bone" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0003861	abnormal nervous system development	"impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs Allelic Composition: Ift88^cbbs/Ift88^tm1.1Bky Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
MP:0003864	abnormal midbrain development	"anomaly in the formation of or the patterning of the part of the brainstem developing from the middle of the three primary cerebral vesicles of the embryo" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0003984	embryonic growth retardation	"slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Ift88^{tm1.1(KOMP)Vlcg}/Ift88^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Ift88^{tm1.1(KOMP)Vlcg}/J Allelic Composition: Ift88^{tm1.1(KOMP)Vlcg}/Ift88⁺ Genetic Background: C57BL/6N-Ift88^{tm1.1(KOMP)Vlcg}/J
MP:0004132	absent embryonic cilia	"absence of cilia on the cells of the embryonic node " [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0004203	abnormal cranial flexure	"any structural abnormality or absence of the sharp, ventrally concave bend in the developing midbrain of the embryo" [J:10730, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: involves: C3HeB/FeJ * C57BL/6J
MP:0004247	small pancreas	"decrease of the size of the pancreas compared to controls" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0004252	abnormal direction of looping morphogenesis	"deviation from the normal rightward direction of cardiac looping" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Ift88^cbbs/Ift88^tm1.1Bky Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
MP:0004276	abnormal medial ganglionic eminence morphology	"any structural anomaly of a distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the neocortex; however, hippocampal neurons, thalamus, septum and olfactory bulb neurons are also partly derived from the MGE" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:12637172]	Show Allelic Composition: Ift88^cbbs/Ift88^tm1.1Bky Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
MP:0004277	abnormal lateral ganglionic eminence morphology	"any structural anomaly of a distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:12637172]	Show Allelic Composition: Ift88^cbbs/Ift88^tm1.1Bky Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
MP:0004574	broad limb buds	"increased anterior-posterior width of the mesenchymal outgrowth on the lateral trunk of the embryo that develops into the limbs" [MESH:National Library of Medicine_Medical Subject Headings]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Bbs7^tm1Vcs/Bbs7^tm1Vcs,Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0004686	decreased length of long bones	"reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
MP:0004789	increased bile salt level	"increased concentration of the steroid salts derived from cholesterol in the liver, produced as bile acids and secreted in the biliary sytem as bile salts; these play an important role in the digestion and absorption of fats" [MESH:D04.808.105, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw
MP:0004924	abnormal behavior	"anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^{tm1.1(KOMP)Vlcg}/Ift88⁺ Genetic Background: C57BL/6N-Ift88^{tm1.1(KOMP)Vlcg}/J
MP:0004986	abnormal osteoblast morphology	"any structural anomaly of a bone-forming cell, which normally forms an osseous matrix (osteoid) in which it becomes enclosed as an osteocyte" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
MP:0005104	abnormal tarsus morphology	"malformation or absence of any of the eight bones of the instep of the paw: tibiale, talus, calcaneus, navicular, 3 cuneiform, and cuboid bones" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0005262	coloboma	"anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs Allelic Composition: Ift88^cbbs/Ift88^tm1.1Bky Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
MP:0005293	impaired glucose tolerance	"less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0005306	abnormal phalanx morphology	"aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0005560	decreased circulating glucose level	"less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0005650	abnormal limb bud morphology	"aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:61460]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N Allelic Composition: Ift88^tm1Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Msx2-cre)5Rem/? Genetic Background: involves: 129P2/OlaHsd Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
MP:0006108	abnormal hindbrain development	"anomaly in the formation or pattering of the caudal region of the brain" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93573]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0006279	abnormal limb development	"anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Bbs7^tm1Vcs/Bbs7^tm1Vcs,Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0006322	abnormal perichondrium morphology	"any structural anomaly of the fibrous connective tissue that surrounds all non-joint end cartilage" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", J:117033, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
MP:0006396	decreased long bone epiphyseal plate size	"reduced size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
MP:0006397	disorganized long bone epiphyseal plate	"a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^tm1Bky/Ift88^tm1.1Bky,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
MP:0008528	polycystic kidney	"the development of innumerable cysts in the kidneys filled with fluid replacing much of the mass of the kidneys leading to reduction in kidney function and frequently kidney failure" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0008986	abnormal liver parenchyma morphology	"any structural anomaly of the functional units of the liver including the lobules" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0009050	dilated proximal convoluted tubules	"stretched or widened aperture of the luminal space of the convoluted portion of the duct system of the nephron that extends from the renal glomerular capsule in the kidney cortex into the kidney medulla where it joins the loop of Henle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: 129/Sv * FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv * FVB/N
MP:0009143	abnormal pancreatic duct morphology	"any structural anomaly of the excretory duct of the exocrine pancreas that collects fluid containing digestive enzymes and transports it to the duodenum" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A03.734.667]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: 129/Sv * FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv * FVB/N
MP:0009145	abnormal pancreatic acinus morphology	"any structural anomaly of the secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0009146	abnormal pancreatic acinar cell morphology	"any structural anomaly of the secretory cells of the exocrine pancreas that produce fluid containing digestive enzymes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0009149	decreased pancreatic acinar cell number	"reduced number of the secretory cells of the exocrine pancreas that produce fluid containing digestive enzymes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0009150	pancreatic acinar cell atrophy	"wasting of the pancreatic acinar cells due to injury or disease, resulting in reduced size or number" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: 129/Sv * FVB/N Allelic Composition: Ift88^Tg737Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv * FVB/N
MP:0009743	preaxial polydactyly	"duplication of all or part of the first ray on one or more of the autopods" [PMID:19125433]	Show Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: involves: C3HeB/FeJ * C57BL/6J Allelic Composition: Ift88^Tg737Rpw/Ift88^tm1Rpw Genetic Background: involves: 129/Sv * FVB/N
MP:0009890	cleft secondary palate	"congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0010041	absent oval cells	"absence of adult liver-specific stem cells; a blast-like cell capable of self renewal and multipotent differentiation, the oval cell is capable of differentiating into mature hepatocytes or cholangiocytes" [PMID:16237666]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw
MP:0010042	abnormal oval cell physiology	"any functional anomaly of adult liver-specific stem cells; a blast-like cell capable of self renewal and multipotent differentiation, the oval cell is capable of differentiating into mature hepatocytes or cholangiocytes" [PMID:16237666]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: C3.FVB-Ift88^Tg737Rpw
MP:0010402	ventricular septal defect	"abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0010403	atrial septal defect	"abnormal communications between the two upper chambers of the heart, including such defects in any or all of the ostium primum, ostium secundum, sinus venosus, and coronary sinus regions" [MESH:C14.240.400.560.375]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0010406	absent atrial septum	"absence of the thin membranous structure between the two heart atria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0010436	abnormal coronary sinus morphology	"any structural anomaly of the short trunk that recieves most of the cardiac veins carrying the blood from the myocardium and delivers it to the right atrium, with the sinoatrial connection occuring between the inferior vena cava and the atrioventricular orifice" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0010440	anomalous pulmonary venous connection	"abnormal development and attachment of the four pulmonary veins that normally attach to the left atrium of the heart, resulting in either partial or complete anomalous drainage back into the systemic venous circulation via an anomalous connection to the right atrium, the superior or inferior vena cava, the innominate vein, the coronary sinus or the left subclavian artery" [http://emedicine.medscape.com]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0010521	absent pulmonary artery	"absence of the artery that arises from the right ventricle and conveys unaerated blood to the lungs" [MESH:A07.231.114.715]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0010773	supernumerary molars	"increased number of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0011066	abnormal renal tubule epithelial cell primary cilium morphology	"any structural anomaly of the single non-motile cilium of a renal tubule epithelial cell that projects into the luminal space of the tubules where it is thought to act as a flow sensor" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:17995581]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: FVB/N-Ift88^Tg737Rpw
MP:0011098	complete embryonic lethality during organogenesis	"death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: involves: C3HeB/FeJ * C57BL/6J Allelic Composition: Ift88^fxo/Ift88^tm1Rpw Genetic Background: involves: 129/Sv * C3HeB/FeJ * C57BL/6J Allelic Composition: Ift88^fxo/Ift88^fxo Genetic Background: C3.B6J-Ift88^fxo Allelic Composition: Bbs7^tm1Vcs/Bbs7^tm1Vcs,Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Ift88^{tm1.1(KOMP)Vlcg}/Ift88^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Ift88^{tm1.1(KOMP)Vlcg}/J
MP:0011108	partial embryonic lethality during organogenesis	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0011109	partial lethality throughout fetal growth and development	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Ift88^cbbs/Ift88^cbbs Genetic Background: B6.Cg-Mapt^tm1(EGFP)Klt Ift88^cbbs
MP:0012531	delayed limb development	"late onset of the induction and/or differentiation of the limbs" [MGI:anna]	Show Allelic Composition: Bbs7^tm1Vcs/Bbs7^tm1Vcs,Ift88^Tg737Rpw/Ift88^Tg737Rpw Genetic Background: involves: FVB/N
MP:0013293	embryonic lethality prior to tooth bud stage	"death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]	Show Allelic Composition: Ift88^{tm1.1(KOMP)Vlcg}/Ift88^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Ift88^{tm1.1(KOMP)Vlcg}/J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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