ENSMUSG00000040380


Mus musculus

Features
Gene ID: ENSMUSG00000040380
  
Biological name :Cbln3
  
Synonyms : Cbln3 / Cerebellin-3 / Q9JHG0
  
Possible biological names infered from orthology : cerebellin 3 precursor / Q6UW01
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C3
Gene start: 55878913
Gene end: 55884392
  
Corresponding Affymetrix probe sets: 10420209 (MoGene1.0st)   1422911_at (Mouse Genome 430 2.0 Array)   1455445_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070494
Ensembl peptide - ENSMUSP00000127798
NCBI entrez gene - 56410     See in Manteia.
MGI - MGI:1889286
RefSeq - NM_019820
RefSeq Peptide - NP_062794
swissprot - Q9JHG0
Ensembl - ENSMUSG00000040380
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CBLN3ENSG00000139899Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cbln2 / Q8BGU2 / Cerebellin-2 / Q8IUK8* / cerebellin 2 precursor*ENSMUSG0000002464756
Cbln1 / Q9R171 / Cerebellin-1 Cerebellin [des-Ser1]-cerebellin / P23435* / cerebellin 1 precursor*ENSMUSG0000003165455
Cbln4 / Q8BME9 / Cerebellin-4 / Q9NTU7* / cerebellin 4 precursor*ENSMUSG0000006757855
Q05A80 / Caprin2 / Q6IMN6* / caprin family member 2*ENSMUSG0000003030931
Q9ES30 / C1qtnf3 / Complement C1q tumor necrosis factor-related protein 3 / Q9BXJ4* / C1QTNF3-AMACR* / C1q and TNF related 3* / C1QTNF3-AMACR readthrough (NMD candidate)*ENSMUSG0000005891431
C1ql4 / Q4ZJM9 / Complement C1q-like protein 4 / Q86Z23* / complement C1q like 4*ENSMUSG0000000107629
C1ql2 / Q8CFR0 / Complement C1q-like protein 2 / Q7Z5L3* / complement C1q like 2*ENSMUSG0000003690727
C1ql3 / Q9ESN4 / Complement C1q-like protein 3 / Q5VWW1* / complement C1q like 3*ENSMUSG0000004963027
C1ql1 / O88992 / C1q-related factor / O75973* / complement C1q like 1*ENSMUSG0000004553227
Q60865 / Caprin1 / Q14444* / cell cycle associated protein 1*ENSMUSG000000271848


Protein motifs (from Interpro)
Interpro ID Name
 IPR001073  C1q domain
 IPR008983  Tumour necrosis factor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IGI
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000886 abnormal cerebellar granule layer "any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Cbln1tm1Jim/Cbln1tm1Jim,Cbln3tm1Jim/Cbln3tm1Jim
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Cbln1tm1Jim/Cbln1tm1Jim,Cbln3tm1Jim/Cbln3tm1Jim
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cbln1tm1Jim/Cbln1tm1Jim,Cbln3tm1Jim/Cbln3tm1Jim
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Cbln1tm1Jim/Cbln1tm1Jim,Cbln3tm1Jim/Cbln3tm1Jim
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cbln1tm1Jim/Cbln1+,Cbln3tm1Jim/Cbln3tm1Jim
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Apba2tm1Tsuz/Apba2tm1Tsuz
Genetic Background: C57BL/6-Apba2tm1Tsuz

Allelic Composition: Cbln1tm1Jim/Cbln1+,Cbln3tm1Jim/Cbln3tm1Jim
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003382 straub tail "condition in which an animal carries its tail in an erect (vertical or nearly vertical) position; often seen upon opioid and other drug treatment" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0003632 abnormal nervous system morphology 
Show

Allelic Composition: Cbln1tm1Jim/Cbln1tm1Jim,Cbln3tm1Jim/Cbln3tm1Jim
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003894 abnormal Purkinje cell innervation "malformation or absence of the supply of nerve fibers that connect to the Purkinje cells" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cbln1tm1Jim/Cbln1tm1Jim,Cbln3tm1Jim/Cbln3tm1Jim
Genetic Background: involves: 129S7/SvEvBrd

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0010507 shortened RR interval "reduction in the length of the interval between an R wave and the next R wave; the RR interval is the inverse of the heart rate" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr