ENSMUSG00000040502


Mus musculus

Features
Gene ID: ENSMUSG00000040502
  
Biological name :March9
  
Synonyms : E3 ubiquitin-protein ligase MARCH9 / March9 / Q3TZ87
  
Possible biological names infered from orthology : membrane associated ring-CH-type finger 9 / Q86YJ5
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 127055011
Gene end: 127060184
  
Corresponding Affymetrix probe sets: 10373021 (MoGene1.0st)   1427409_at (Mouse Genome 430 2.0 Array)   1437366_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041581
NCBI entrez gene - 216438     See in Manteia.
MGI - MGI:2446144
RefSeq - NM_001033262
RefSeq Peptide - NP_001028434
swissprot - Q3TZ87
Ensembl - ENSMUSG00000040502
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 march9ENSDARG00000055740Danio rerio
 MARCH9ENSG00000139266Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
March4 / Q80TE3 / E3 ubiquitin-protein ligase MARCH4 / Q9P2E8* / membrane associated ring-CH-type finger 4*ENSMUSG0000003937263
Q8CBH7 / March11 / E3 ubiquitin-protein ligase MARCH11 / A6NNE9* / membrane associated ring-CH-type finger 11*ENSMUSG0000002226945
March1 / Q6NZQ8 / E3 ubiquitin-protein ligase MARCH1 / Q8TCQ1* / membrane associated ring-CH-type finger 1*ENSMUSG0000003646918
March8 / Q9DBD2 / E3 ubiquitin-protein ligase MARCH8 / Q5T0T0* / membrane associated ring-CH-type finger 8*ENSMUSG0000002570216
March2 / Q99M02 / E3 ubiquitin-protein ligase MARCH2 / Q9P0N8* / membrane associated ring-CH-type finger 2*ENSMUSG0000007955712
March3 / Q8BRX9 / E3 ubiquitin-protein ligase MARCH3 / Q86UD3* / membrane associated ring-CH-type finger 3*ENSMUSG0000003265611


Protein motifs (from Interpro)
Interpro ID Name
 IPR011016  Zinc finger, RING-CH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR033275  E3 ubiquitin-protein ligase MARCH-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000186 decreased circulating HDL cholesterol level "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

 MP:0001391 abnormal tail movements "a change from the normal manner of moving the tail" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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