ENSMUSG00000025702


Mus musculus

Features
Gene ID: ENSMUSG00000025702
  
Biological name :March8
  
Synonyms : E3 ubiquitin-protein ligase MARCH8 / March8 / Q9DBD2
  
Possible biological names infered from orthology : membrane associated ring-CH-type finger 8 / Q5T0T0
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: E3
Gene start: 116338024
Gene end: 116409540
  
Corresponding Affymetrix probe sets: 10541049 (MoGene1.0st)   1428385_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000144936
Ensembl peptide - ENSMUSP00000115510
Ensembl peptide - ENSMUSP00000145054
Ensembl peptide - ENSMUSP00000145351
Ensembl peptide - ENSMUSP00000145270
Ensembl peptide - ENSMUSP00000145237
Ensembl peptide - ENSMUSP00000145137
Ensembl peptide - ENSMUSP00000145060
Ensembl peptide - ENSMUSP00000078024
Ensembl peptide - ENSMUSP00000098594
NCBI entrez gene - 71779     See in Manteia.
MGI - MGI:1919029
RefSeq - XM_017321749
RefSeq - NM_001302384
RefSeq - NM_001302385
RefSeq - NM_027920
RefSeq - XM_006506638
RefSeq - XM_006506639
RefSeq - XM_006506640
RefSeq - XM_006506641
RefSeq - XM_006506642
RefSeq - XM_006506643
RefSeq - XM_006506645
RefSeq - XM_006506648
RefSeq - XM_011241469
RefSeq - XM_011241470
RefSeq - NM_001302383
RefSeq Peptide - NP_001289314
RefSeq Peptide - NP_082196
RefSeq Peptide - NP_001289312
RefSeq Peptide - NP_001289313
swissprot - A0A0N4SVD9
swissprot - F6THH9
swissprot - A0A0N4SW32
swissprot - Q9DBD2
swissprot - A0A0N4SV35
swissprot - A0A0N4SVD4
swissprot - A0A0N4SVW5
swissprot - A0A0N4SVT6
swissprot - A0A0N4SVK0
Ensembl - ENSMUSG00000025702
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 march8ENSDARG00000062489Danio rerio
 MARCH8ENSGALG00000005867Gallus gallus
 MARCH8ENSG00000165406Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
March1 / Q6NZQ8 / E3 ubiquitin-protein ligase MARCH1 / Q8TCQ1* / membrane associated ring-CH-type finger 1*ENSMUSG0000003646965
March2 / Q99M02 / E3 ubiquitin-protein ligase MARCH2 / Q9P0N8* / membrane associated ring-CH-type finger 2*ENSMUSG0000007955721
March9 / Q3TZ87 / E3 ubiquitin-protein ligase MARCH9 / Q86YJ5* / membrane associated ring-CH-type finger 9*ENSMUSG0000004050220
March4 / Q80TE3 / E3 ubiquitin-protein ligase MARCH4 / Q9P2E8* / membrane associated ring-CH-type finger 4*ENSMUSG0000003937219
March3 / Q8BRX9 / E3 ubiquitin-protein ligase MARCH3 / Q86UD3* / membrane associated ring-CH-type finger 3*ENSMUSG0000003265618
Q8CBH7 / March11 / E3 ubiquitin-protein ligase MARCH11 / A6NNE9* / membrane associated ring-CH-type finger 11*ENSMUSG0000002226917


Protein motifs (from Interpro)
Interpro ID Name
 IPR011016  Zinc finger, RING-CH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR033275  E3 ubiquitin-protein ligase MARCH-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination ISO
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002495 antigen processing and presentation of peptide antigen via MHC class II IDA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0045347 negative regulation of MHC class II biosynthetic process IDA
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042289 MHC class II protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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