ENSG00000165406


Homo sapiens

Features
Gene ID: ENSG00000165406
  
Biological name :MARCH8
  
Synonyms : MARCH8 / membrane associated ring-CH-type finger 8 / Q5T0T0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q11.22
Gene start: 45454585
Gene end: 45594906
  
Corresponding Affymetrix probe sets: 221824_s_at (Human Genome U133 Plus 2.0 Array)   231933_at (Human Genome U133 Plus 2.0 Array)   236056_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396678
Ensembl peptide - ENSP00000411848
Ensembl peptide - ENSP00000317087
Ensembl peptide - ENSP00000379116
NCBI entrez gene - 220972     See in Manteia.
OMIM - 613335
RefSeq - XM_017015894
RefSeq - XM_005271804
RefSeq - XM_006717704
RefSeq - XM_011539492
RefSeq - XM_011539493
RefSeq - XM_011539494
RefSeq - XM_011539495
RefSeq - NM_001002266
RefSeq - NM_001282866
RefSeq - NM_145021
RefSeq Peptide - NP_659458
RefSeq Peptide - NP_001002266
RefSeq Peptide - NP_001269795
swissprot - A0A0A0MSM7
swissprot - Q5T0T0
swissprot - A0A024R7U2
Ensembl - ENSG00000165406
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 march8ENSDARG00000062489Danio rerio
 MARCH8ENSGALG00000005867Gallus gallus
 March8ENSMUSG00000025702Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MARCH1 / Q8TCQ1 / membrane associated ring-CH-type finger 1ENSG0000014541633
MARCH4 / Q9P2E8 / membrane associated ring-CH-type finger 4ENSG0000014458313
MARCH9 / Q86YJ5 / membrane associated ring-CH-type finger 9ENSG0000013926612
MARCH2 / Q9P0N8 / membrane associated ring-CH-type finger 2ENSG0000009978512
A6NNE9 / MARCH11 / membrane associated ring-CH-type finger 11ENSG0000018365412
MARCH3 / Q86UD3 / membrane associated ring-CH-type finger 3ENSG0000017392611


Protein motifs (from Interpro)
Interpro ID Name
 IPR011016  Zinc finger, RING-CH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR033275  E3 ubiquitin-protein ligase MARCH-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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