ENSG00000145416


Homo sapiens

Features
Gene ID: ENSG00000145416
  
Biological name :MARCH1
  
Synonyms : MARCH1 / membrane associated ring-CH-type finger 1 / Q8TCQ1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q32.3
Gene start: 163524298
Gene end: 164384050
  
Corresponding Affymetrix probe sets: 1562338_at (Human Genome U133 Plus 2.0 Array)   219574_at (Human Genome U133 Plus 2.0 Array)   229383_at (Human Genome U133 Plus 2.0 Array)   235385_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000345676
Ensembl peptide - ENSP00000427223
Ensembl peptide - ENSP00000426731
Ensembl peptide - ENSP00000424089
Ensembl peptide - ENSP00000421322
Ensembl peptide - ENSP00000274056
NCBI entrez gene - 55016     See in Manteia.
OMIM - 613331
RefSeq - XM_011532055
RefSeq - XM_017008335
RefSeq - XM_017008336
RefSeq - NM_001166373
RefSeq - NM_017923
RefSeq - XM_017008334
RefSeq Peptide - NP_001159845
RefSeq Peptide - NP_060393
swissprot - Q8TCQ1
swissprot - D6RGC4
swissprot - B7Z739
swissprot - D6REN1
Ensembl - ENSG00000145416
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BX470214.1ENSDARG00000110724Danio rerio
 march1ENSDARG00000037487Danio rerio
 MARCH1ENSGALG00000009520Gallus gallus
 March1ENSMUSG00000036469Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MARCH8 / Q5T0T0 / membrane associated ring-CH-type finger 8ENSG0000016540665
MARCH2 / Q9P0N8 / membrane associated ring-CH-type finger 2ENSG0000009978523
MARCH3 / Q86UD3 / membrane associated ring-CH-type finger 3ENSG0000017392622
MARCH4 / Q9P2E8 / membrane associated ring-CH-type finger 4ENSG0000014458321
MARCH9 / Q86YJ5 / membrane associated ring-CH-type finger 9ENSG0000013926620
A6NNE9 / MARCH11 / membrane associated ring-CH-type finger 11ENSG0000018365418


Protein motifs (from Interpro)
Interpro ID Name
 IPR011016  Zinc finger, RING-CH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR033275  E3 ubiquitin-protein ligase MARCH-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002495 antigen processing and presentation of peptide antigen via MHC class II IDA
 biological_processGO:0006955 immune response IDA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane ISS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0032588 trans-Golgi network membrane ISS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042287 MHC protein binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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