ENSMUSG00000040612


Mus musculus

Features
Gene ID: ENSMUSG00000040612
  
Biological name :Ildr2
  
Synonyms : B5TVM2 / Ildr2 / Immunoglobulin-like domain-containing receptor 2
  
Possible biological names infered from orthology : Q71H61
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H2.3
Gene start: 166254139
Gene end: 166316823
  
Corresponding Affymetrix probe sets: 10351380 (MoGene1.0st)   1436221_at (Mouse Genome 430 2.0 Array)   1436293_x_at (Mouse Genome 430 2.0 Array)   1436894_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107047
Ensembl peptide - ENSMUSP00000142311
Ensembl peptide - ENSMUSP00000142240
Ensembl peptide - ENSMUSP00000142152
Ensembl peptide - ENSMUSP00000141961
Ensembl peptide - ENSMUSP00000141502
Ensembl peptide - ENSMUSP00000141323
NCBI entrez gene - 100039795     See in Manteia.
MGI - MGI:1196370
RefSeq - XM_011238731
RefSeq - XM_006496596
RefSeq - XM_006496595
RefSeq - XM_006496594
RefSeq - XM_006496593
RefSeq - NM_001164528
RefSeq Peptide - NP_001158000
RefSeq Peptide - NP_001344357
RefSeq Peptide - NP_001344358
RefSeq Peptide - NP_001344359
swissprot - A0A0A6YY19
swissprot - A0A0A6YY76
swissprot - A0A0A6YWD2
swissprot - A0A0A6YXF0
swissprot - A0A0A6YVY9
swissprot - B5TVM2
swissprot - A0A0A6YXV2
Ensembl - ENSMUSG00000040612
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ildr2ENSDARG00000014180Danio rerio
 si:zfos-1011f11.2ENSDARG00000101073Danio rerio
 ILDR2ENSGALG00000015458Gallus gallus
 ILDR2ENSG00000143195Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lsr / Q99KG5 / Lipolysis-stimulated lipoprotein receptor / Q86X29*ENSMUSG0000000124731
Ildr1 / Q8CBR1 / Immunoglobulin-like domain-containing receptor 1 / Q86SU0*ENSMUSG0000002290021


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR008664  LISCH7
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009749 response to glucose IMP
 biological_processGO:0030073 insulin secretion IMP
 biological_processGO:0030154 cell differentiation IMP
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001559 hyperglycemia "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pomctm1Low/Pomctm1Low
Genetic Background: B6.129S2-Pomctm1Low

Allelic Composition: Ildr2Dbsm1-DBA/2J/Ildr2Dbsm1-DBA/2J
Genetic Background: B6.D2-Ildr2Dbsm1-DBA/2J

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ildr2Dbsm1-DBA/2J/Ildr2Dbsm1-DBA/2J,Lepob/Lepob
Genetic Background: B6.Cg-Ildr2Dbsm1-DBA/2J Lepob

Allelic Composition: Ildr2W87*/Ildr2W87*
Genetic Background: involves: C3HeB/FeJ

 MP:0003339 decreased number of pancreatic beta cells "fewer than normal number of the cells of the pancreas that secrete insulin" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ildr2W87*/Ildr2W87*
Genetic Background: involves: C3HeB/FeJ

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ildr2Dbsm1-DBA/2J/Ildr2Dbsm1-DBA/2J,Lepob/Lepob
Genetic Background: B6.Cg-Ildr2Dbsm1-DBA/2J Lepob

Allelic Composition: Ildr2W87*/Ildr2W87*
Genetic Background: involves: C3HeB/FeJ

 MP:0009114 decreased pancreatic beta cell mass "reduced total physical bulk or volume of a pancreatic beta cell compared to the normal state" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ildr2Dbsm1-DBA/2J/Ildr2Dbsm1-DBA/2J,Lepob/Lepob
Genetic Background: B6.Cg-Ildr2Dbsm1-DBA/2J Lepob

Allelic Composition: Ildr2W87*/Ildr2W87*
Genetic Background: involves: C3HeB/FeJ

 MP:0009175 abnormal pancreatic beta cell differentiation "atypical production of or inability to produce the cells of the pancreas that secrete insulin, and/or accumulation of pancreatic beta cell precursors" [MESH:A03.734.414.131]
Show

Allelic Composition: Ildr2W87*/Ildr2W87*
Genetic Background: involves: C3HeB/FeJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr