ENSMUSG00000040661


Mus musculus

Features
Gene ID: ENSMUSG00000040661
  
Biological name :Rad54l2
  
Synonyms : Rad54l2 / RAD54 like 2 (S. cerevisiae)
  
Possible biological names infered from orthology : Q9Y4B4 / RAD54 like 2
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F1
Gene start: 106688082
Gene end: 106789194
  
Corresponding Affymetrix probe sets: 10596543 (MoGene1.0st)   10596545 (MoGene1.0st)   1423485_at (Mouse Genome 430 2.0 Array)   1454910_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045454
Ensembl peptide - ENSMUSP00000139803
Ensembl peptide - ENSMUSP00000139687
NCBI entrez gene - 81000     See in Manteia.
MGI - MGI:1933196
RefSeq - NM_030730
RefSeq Peptide - NP_109655
swissprot - E9QKL0
swissprot - A0A087WPJ6
swissprot - A0A087WP96
Ensembl - ENSMUSG00000040661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rad54l2ENSDARG00000063031Danio rerio
 RAD54L2ENSGALG00000003243Gallus gallus
 Q9Y4B4ENSG00000164080Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Atrx / Q61687 / Transcriptional regulator ATRX / P46100* / ATRX, chromatin remodeler*ENSMUSG0000003122925
P70270 / Rad54l / DNA repair and recombination protein RAD54-like / Q92698* / RAD54 like*ENSMUSG0000002870214
Q6PFE3 / Rad54b / DNA repair and recombination protein RAD54B / FSBP* / O95073* / Q9Y620* / RAD54 homolog B (S. cerevisiae)* / fibrinogen silencer binding protein*ENSMUSG0000007877314


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001650  Helicase, C-terminal
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0011704 decreased fibroblast proliferation "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0012505 increased neural tube apoptosis "increase in the number of cells of the neural tube undergoing programmed cell death" [MGI:anna]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0012706 decreased embryonic neuroepithelial cell proliferation "decrease in the expansion rate of the cells of the embryonic neuroepithelium by cell division" [CL:0000710, MGI:anna]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

 MP:0013501 increased fibroblast apoptosis "increase in the timing or the number of fibroblast cells undergoing programmed cell death" [MGI:csmith]
Show

Allelic Composition: Il12btm2Lky/Il12btm2Lky
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * BALB/c * C57BL/6J)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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