ENSMUSG00000041073


Mus musculus

Features
Gene ID: ENSMUSG00000041073
  
Biological name :Nacad
  
Synonyms : Nacad / NAC-alpha domain-containing protein 1 / Q5SWP3
  
Possible biological names infered from orthology : NAC alpha domain containing / O15069
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A1
Gene start: 6597823
Gene end: 6606053
  
Corresponding Affymetrix probe sets: 10384183 (MoGene1.0st)   1440480_at (Mouse Genome 430 2.0 Array)   1455509_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135338
Ensembl peptide - ENSMUSP00000049490
Ensembl peptide - ENSMUSP00000134974
NCBI entrez gene - 192950     See in Manteia.
MGI - MGI:3603030
RefSeq - NM_001081652
RefSeq Peptide - NP_001075121
swissprot - Q5SWP3
swissprot - H3BJG2
swissprot - H3BKC6
Ensembl - ENSMUSG00000041073
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nacadENSDARG00000012347Danio rerio
 ENSGALG00000037608Gallus gallus
 NACADENSG00000136274Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Naca / Q60817 / P70670 / Nascent polypeptide-associated complex subunit alpha, muscle-specific form / NACA2* / Q9H009* / nascent polypeptide associated complex alpha subunit 2*ENSMUSG0000006131517


Protein motifs (from Interpro)
Interpro ID Name
 IPR002715  Nascent polypeptide-associated complex NAC domain
 IPR016641  Nascent polypeptide-associated complex subunit alpha


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005854 nascent polypeptide-associated complex IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

 MP:0005633 increased circulating sodium level "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

 MP:0010101 increased sacral vertebrae number "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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