ENSMUSG00000041313


Mus musculus

Features
Gene ID: ENSMUSG00000041313
  
Biological name :Slc7a1
  
Synonyms : Q09143 / Slc7a1 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
  
Possible biological names infered from orthology : P30825 / solute carrier family 7 member 1
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G3
Gene start: 148327410
Gene end: 148399904
  
Corresponding Affymetrix probe sets: 10535852 (MoGene1.0st)   1421533_at (Mouse Genome 430 2.0 Array)   1454991_at (Mouse Genome 430 2.0 Array)   1454992_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117781
Ensembl peptide - ENSMUSP00000144000
Ensembl peptide - ENSMUSP00000122914
Ensembl peptide - ENSMUSP00000046714
NCBI entrez gene - 11987     See in Manteia.
MGI - MGI:88117
RefSeq - NM_001301424
RefSeq - XM_006504796
RefSeq - NM_007513
RefSeq Peptide - NP_001288353
RefSeq Peptide - NP_031539
swissprot - E9Q3N1
swissprot - D3Z161
swissprot - Q09143
swissprot - Q3UGD6
swissprot - A0A0J9YU45
Ensembl - ENSMUSG00000041313
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc7a1ENSDARG00000016439Danio rerio
 SLC7A1 (1 of many)ENSDARG00000100227Danio rerio
 SLC7A1ENSGALG00000017085Gallus gallus
 P30825ENSG00000139514Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P18581 / Slc7a2 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 / P52569* / solute carrier family 7 member 2*ENSMUSG0000003159661
P70423 / Slc7a3 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 / Q8WY07* / solute carrier family 7 member 3*ENSMUSG0000003129758
AU018091 / expressed sequence AU018091ENSMUSG0000005475355
Q8BXR1 / Slc7a14 / Probable cationic amino acid transporter / Q8TBB6* / solute carrier family 7 member 14*ENSMUSG0000006907243
Q8BLQ7 / Slc7a4 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 / O43246* / solute carrier family 7 member 4*ENSMUSG0000002275639


Protein motifs (from Interpro)
Interpro ID Name
 IPR002293  Amino acid/polyamine transporter I
 IPR004755  Cationic amino acid transport permease
 IPR029485  Cationic amino acid transporter, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006865 amino acid transport IEA
 biological_processGO:0015809 arginine transport IDA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1903826 arginine transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015181 arginine transmembrane transporter activity IDA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0002416 abnormal proerythroblast morphology/development "anomalous structure, formation, or numbers of the immature, nucleated erythrocyte precursors that give rise to reticulocytes " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0002424 abnormal reticulocyte morphology/development "anomalous structure, formation, or numbers of immature erthrocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0002641 anisopoikilocytosis "presence in blood of RBCs of abnormal shapes and sizes" [J:78271, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0002874 decreased hemoglobin content "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0005562 decreased mean corpuscular hemoglobin "less than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0009395 persistence of primitive erythrocytes "presence of increased numbers of nucleated red blood cells at stages when these cells are normally replaced by mature, enucleated, red blood cells" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Cxcr2tm1Mwm/Cxcr2tm1Mwm
Genetic Background: C.129S2(B6)-Cxcr2tm1Mwm/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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