ENSMUSG00000031596


Mus musculus

Features
Gene ID: ENSMUSG00000031596
  
Biological name :Slc7a2
  
Synonyms : P18581 / Slc7a2 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
  
Possible biological names infered from orthology : P52569 / solute carrier family 7 member 2
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A4
Gene start: 40862396
Gene end: 40922308
  
Corresponding Affymetrix probe sets: 10571444 (MoGene1.0st)   1422648_at (Mouse Genome 430 2.0 Array)   1426008_a_at (Mouse Genome 430 2.0 Array)   1436555_at (Mouse Genome 430 2.0 Array)   1450703_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058866
Ensembl peptide - ENSMUSP00000112848
Ensembl peptide - ENSMUSP00000113729
Ensembl peptide - ENSMUSP00000114675
Ensembl peptide - ENSMUSP00000096414
NCBI entrez gene - 11988     See in Manteia.
MGI - MGI:99828
RefSeq - XM_006509253
RefSeq - NM_001044740
RefSeq - NM_007514
RefSeq - XM_006509250
RefSeq - XM_006509251
RefSeq - XM_006509252
RefSeq Peptide - NP_001038205
RefSeq Peptide - NP_031540
swissprot - E9QJY0
swissprot - P18581
swissprot - A0A1C7ZMY5
Ensembl - ENSMUSG00000031596
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc7a2ENSDARG00000037097Danio rerio
 SLC7A2ENSGALG00000013627Gallus gallus
 P52569ENSG00000003989Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q09143 / Slc7a1 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 / P30825* / solute carrier family 7 member 1*ENSMUSG0000004131357
P70423 / Slc7a3 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 / Q8WY07* / solute carrier family 7 member 3*ENSMUSG0000003129751
AU018091 / expressed sequence AU018091ENSMUSG0000005475349
Q8BXR1 / Slc7a14 / Probable cationic amino acid transporter / Q8TBB6* / solute carrier family 7 member 14*ENSMUSG0000006907242
Q8BLQ7 / Slc7a4 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 / O43246* / solute carrier family 7 member 4*ENSMUSG0000002275637


Protein motifs (from Interpro)
Interpro ID Name
 IPR002293  Amino acid/polyamine transporter I
 IPR004755  Cationic amino acid transport permease
 IPR029485  Cationic amino acid transporter, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002537 nitric oxide production involved in inflammatory response IMP
 biological_processGO:0006809 nitric oxide biosynthetic process IMP
 biological_processGO:0006865 amino acid transport IEA
 biological_processGO:0015809 arginine transport IEA
 biological_processGO:0042116 macrophage activation IMP
 biological_processGO:0043030 regulation of macrophage activation IMP
 biological_processGO:0050727 regulation of inflammatory response IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0097638 L-arginine import across plasma membrane IDA
 biological_processGO:0097639 L-lysine import across plasma membrane IDA
 biological_processGO:0097640 L-ornithine import across plasma membrane IDA
 biological_processGO:1902023 L-arginine transport IMP
 biological_processGO:1903352 L-ornithine transmembrane transport IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0000064 L-ornithine transmembrane transporter activity IDA
 molecular_functionGO:0005289 high-affinity arginine transmembrane transporter activity IDA
 molecular_functionGO:0005292 high-affinity lysine transmembrane transporter activity IDA
 molecular_functionGO:0015181 arginine transmembrane transporter activity IMP
 molecular_functionGO:0015189 L-lysine transmembrane transporter activity IDA
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0061459 L-arginine transmembrane transporter activity IMP
 molecular_functionGO:0097626 low-affinity L-arginine transmembrane transporter activity IDA
 molecular_functionGO:0097627 high-affinity L-ornithine transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001790 abnormal immune system physiology "deviation from the normal function of the immune system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tnctm1Sia/Tnctm1Sia
Genetic Background: involves: BALB/c * C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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