ENSMUSG00000069072


Mus musculus

Features
Gene ID: ENSMUSG00000069072
  
Biological name :Slc7a14
  
Synonyms : Probable cationic amino acid transporter / Q8BXR1 / Slc7a14
  
Possible biological names infered from orthology : Q8TBB6 / solute carrier family 7 member 14
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: A3
Gene start: 31202858
Gene end: 31310378
  
Corresponding Affymetrix probe sets: 10497663 (MoGene1.0st)   1439607_at (Mouse Genome 430 2.0 Array)   1456187_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103880
Ensembl peptide - ENSMUSP00000088803
NCBI entrez gene - 241919     See in Manteia.
MGI - MGI:3040688
RefSeq - NM_172861
RefSeq - XM_006535472
RefSeq Peptide - NP_766449
swissprot - D3YY38
swissprot - Q8BXR1
Ensembl - ENSMUSG00000069072
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0UYF2ENSDARG00000010816Danio rerio
 slc7a14bENSDARG00000079231Danio rerio
 SLC7A14ENSGALG00000009349Gallus gallus
 Q8TBB6ENSG00000013293Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P18581 / Slc7a2 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 / P52569* / solute carrier family 7 member 2*ENSMUSG0000003159636
Q09143 / Slc7a1 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 / P30825* / solute carrier family 7 member 1*ENSMUSG0000004131335
P70423 / Slc7a3 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 / Q8WY07* / solute carrier family 7 member 3*ENSMUSG0000003129734
AU018091 / expressed sequence AU018091ENSMUSG0000005475333
Q8BLQ7 / Slc7a4 / solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 / O43246* / solute carrier family 7 member 4*ENSMUSG0000002275632


Protein motifs (from Interpro)
Interpro ID Name
 IPR002293  Amino acid/polyamine transporter I
 IPR029485  Cationic amino acid transporter, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006865 amino acid transport IEA
 biological_processGO:0010923 negative regulation of phosphatase activity IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0011965 decreased total retina thickness "decreased width of the retina through the center plane" [MGI:csmith]
Show

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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