ENSMUSG00000041481


Mus musculus

Features
Gene ID: ENSMUSG00000041481
  
Biological name :Serpina3g
  
Synonyms : serine (or cysteine) peptidase inhibitor, clade A, member 3G / Serpina3g
  
Possible biological names infered from orthology : P01011 / SERPINA3 / serpin family A member 3
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: E
Gene start: 104236245
Gene end: 104241939
  
Corresponding Affymetrix probe sets: 1424923_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126548
Ensembl peptide - ENSMUSP00000041250
Ensembl peptide - ENSMUSP00000129633
NCBI entrez gene - 20715     See in Manteia.
MGI - MGI:105046
RefSeq - NM_001353612
RefSeq - NM_009251
RefSeq Peptide - NP_033277
RefSeq Peptide - NP_001340541
swissprot - E9Q499
swissprot - F2Z405
Ensembl - ENSMUSG00000041481
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 serpina1ENSDARG00000090286Danio rerio
 serpina1lENSDARG00000090850Danio rerio
 serpina7ENSDARG00000087143Danio rerio
 si:ch211-186e20.2ENSDARG00000074712Danio rerio
 si:ch211-186e20.7ENSDARG00000077960Danio rerio
 zgc:174259ENSDARG00000091136Danio rerio
 ENSGALG00000028598Gallus gallus
 ENSGALG00000046409Gallus gallus
 ENSGALG00000020390Gallus gallus
 ENSGALG00000020388Gallus gallus
 SPIA1ENSGALG00000023070Gallus gallus
 SPIA4ENSGALG00000010969Gallus gallus
 P01011ENSG00000196136Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80X76 / Serpina3f / Serine protease inhibitor A3F / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000006636377
Serpina3n / serine (or cysteine) peptidase inhibitor, clade A, member 3N / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000002109169
Serpina3i / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000007901469
Q03734 / Serpina3m / Serine protease inhibitor A3M / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000007901266
P29621 / Serpina3c / Serine protease inhibitor A3C / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000006636165
Serpina3k / serine (or cysteine) peptidase inhibitor, clade A, member 3K / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000005820762
Q6P4P1 / Serpina3a / serine (or cysteine) peptidase inhibitor, clade A, member 3A / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000004153650
Q8BYY9 / Serpina3b / serine (or cysteine) peptidase inhibitor, clade A, member 3B / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000006636449
Serpina3j / serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J / P01011* / SERPINA3* / serpin family A member 3*ENSMUSG0000007901349
Serpina11 / serpin family A member 11 / Q86U17*ENSMUSG0000006323239
Q00898 / Serpina1e / serine (or cysteine) peptidase inhibitor, clade A, member 1E / P01009* / SERPINA1* / serpin family A member 1*ENSMUSG0000007284939
Q9D7D2 / Serpina9 / serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 / Q86WD7* / serpin family A member 9*ENSMUSG0000005826039
P70458 / Serpina5 / serine (or cysteine) peptidase inhibitor, clade A, member 5 / P05154* / serpin family A member 5*ENSMUSG0000004155038
Serpina1c / serine (or cysteine) peptidase inhibitor, clade A, member 1C / P01009* / SERPINA1* / serpin family A member 1*ENSMUSG0000007901537
P07758 / Serpina1a / serine (or cysteine) peptidase inhibitor, clade A, member 1A / P01009* / SERPINA1* / serpin family A member 1*ENSMUSG0000006636636
P22599 / Serpina1b / serine (or cysteine) preptidase inhibitor, clade A, member 1B / P01009* / SERPINA1* / serpin family A member 1*ENSMUSG0000007117836
Q00897 / Serpina1d / serine (or cysteine) peptidase inhibitor, clade A, member 1D / P01009* / SERPINA1* / serpin family A member 1*ENSMUSG0000007117735
Serpina7 / serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 / P05543* / serpin family A member 7*ENSMUSG0000003127133
Q7TMF5 / Serpina12 / Serpin A12 / Q8IW75* / serpin family A member 12*ENSMUSG0000004156731
Q06770 / Serpina6 / serine (or cysteine) peptidase inhibitor, clade A, member 6 / P08185* / serpin family A member 6*ENSMUSG0000006080730


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005615 extracellular space IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005025 response to infection "the body s reaction to invasion and multiplication of microorganisms in its tissues, or the body s reaction to components of or toxins produced by pathogenic mircroorganisms " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nlrp3tm1Bhk/Nlrp3tm1Bhk
Genetic Background: involves: 129S6/SvEvTac

 MP:0005095 decreased T cell proliferation "reduced clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Nlrp3tm1Bhk/Nlrp3tm1Bhk
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Serpina3gtm1.1Arp/Serpina3gtm1.1Arp,Tg(TcrLCMV)#Sdz/0
Genetic Background: involves: C57BL/6 * DBA/2

 MP:0010833 abnormal memory T cell morphology "any structural anomaly of distinctly differentiated long-lived T cells that have the phenotype CD45RO-positive and CD127-positive" [CL:0000813, GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, ISBN:0781735149]
Show

Allelic Composition: Nlrp3tm1Bhk/Nlrp3tm1Bhk
Genetic Background: involves: 129S6/SvEvTac

 MP:0010839 decreased CD8-positive, alpha-beta memory T cell number "decreased number of CD8-positive, alpha-beta T cells with memory phenotype indicated by being CD45RO and CD127-positive, or also described as being CD25-negative, CD44-high, and CD122- high" [CL:0000909, GO_REF:0000031, GOC:tfm, PMID:20146720]
Show

Allelic Composition: Nlrp3tm1Bhk/Nlrp3tm1Bhk
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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