ENSMUSG00000041594


Mus musculus

Features
Gene ID: ENSMUSG00000041594
  
Biological name :Tmtc4
  
Synonyms : Q8BG19 / Tmtc4 / Transmembrane and TPR repeat-containing protein 4
  
Possible biological names infered from orthology : Q5T4D3 / transmembrane and tetratricopeptide repeat containing 4
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: E5
Gene start: 122918971
Gene end: 122984035
  
Corresponding Affymetrix probe sets: 10422518 (MoGene1.0st)   1428113_at (Mouse Genome 430 2.0 Array)   1432360_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046368
Ensembl peptide - ENSMUSP00000116480
Ensembl peptide - ENSMUSP00000118814
Ensembl peptide - ENSMUSP00000121523
Ensembl peptide - ENSMUSP00000116379
NCBI entrez gene - 70551     See in Manteia.
MGI - MGI:1921050
RefSeq - XM_017316185
RefSeq - XM_006519512
RefSeq - XM_017316182
RefSeq - XM_017316183
RefSeq - XM_017316184
RefSeq - NM_028651
RefSeq - XM_006519509
RefSeq - XM_006519510
RefSeq - XM_006519511
RefSeq Peptide - NP_082927
swissprot - D6RHA9
swissprot - D6RH66
swissprot - Q8BG19
Ensembl - ENSMUSG00000041594
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmtc4ENSDARG00000020447Danio rerio
 TMTC4ENSGALG00000016870Gallus gallus
 TMTC4ENSG00000125247Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tmtc1 / Q3UV71 / Mus musculus transmembrane and tetratricopeptide repeat containing 1 (Tmtc1), transcript variant 2, mRNA. / Q8IUR5* / transmembrane and tetratricopeptide repeat containing 1*ENSMUSG0000003030636
Tmtc3 / transmembrane and tetratricopeptide repeat containing 3 / Q6ZXV5*ENSMUSG0000003667635
Tmtc2 / Q56A06 / transmembrane and tetratricopeptide repeat containing 2 / Q8N394*ENSMUSG0000003601933
Ogt / Q8CGY8 / UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit / O15294* / O-linked N-acetylglucosamine (GlcNAc) transferase*ENSMUSG0000003416016


Protein motifs (from Interpro)
Interpro ID Name
 IPR001440  Tetratricopeptide repeat 1
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR013618  Domain of unknown function DUF1736
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
Show

Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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