ENSMUSG00000043079


Mus musculus

Features
Gene ID: ENSMUSG00000043079
  
Biological name :Synpo
  
Synonyms : Q8CC35 / Synaptopodin / Synpo
  
Possible biological names infered from orthology : Q8N3V7
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: D3
Gene start: 60593973
Gene end: 60660142
  
Corresponding Affymetrix probe sets: 10459084 (MoGene1.0st)   1427045_at (Mouse Genome 430 2.0 Array)   1434089_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124122
Ensembl peptide - ENSMUSP00000121756
Ensembl peptide - ENSMUSP00000125272
Ensembl peptide - ENSMUSP00000095174
Ensembl peptide - ENSMUSP00000110973
Ensembl peptide - ENSMUSP00000115355
Ensembl peptide - ENSMUSP00000117897
NCBI entrez gene - 104027     See in Manteia.
MGI - MGI:1099446
RefSeq - XM_006525476
RefSeq - NM_177340
RefSeq - XM_006525468
RefSeq - XM_006525470
RefSeq - XM_006525471
RefSeq - XM_006525472
RefSeq - XM_006525474
RefSeq - XM_006525475
RefSeq - NM_001109975
RefSeq Peptide - NP_001103445
RefSeq Peptide - NP_796314
swissprot - E0CYK1
swissprot - E9Q3E2
swissprot - Q3URF1
swissprot - Q3U336
swissprot - Q8CC35
Ensembl - ENSMUSG00000043079
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO018188.1ENSDARG00000106873Danio rerio
 SYNPOENSGALG00000027330Gallus gallus
 SYNPOENSG00000171992Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91YE8 / Synpo2 / Synaptopodin-2 / Q9UMS6*ENSMUSG0000005031522
Q8BWB1 / Synpo2l / synaptopodin 2-like / Q9H987*ENSMUSG0000003937617


Protein motifs (from Interpro)
Interpro ID Name
 IPR028753  Synaptopodin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008542 visual learning IMP
 biological_processGO:0030865 cortical cytoskeleton organization NAS
 biological_processGO:0032233 positive regulation of actin filament bundle assembly IEA
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity IMP
 biological_processGO:0098886 modification of dendritic spine ISO
 biological_processGO:1905355 spine apparatus assembly IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030018 Z disc IBA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine NAS
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0097444 spine apparatus IDA
 molecular_functionGO:0003779 actin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000934 abnormal telencephalon development "malformed or incomplete differentiation of the anterior division of the embryonic prosencephalon " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:49840]
Show

Allelic Composition: Ccne2tm1Pisc/Ccne2tm1Pisc
Genetic Background: involves: 129S2/SvPas

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
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Allelic Composition: Ccne2tm1Pisc/Ccne2tm1Pisc
Genetic Background: involves: 129S2/SvPas

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Ccne2tm1Pisc/Ccne2tm1Pisc
Genetic Background: involves: 129S2/SvPas

 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Ccne2tm1Pisc/Ccne2tm1Pisc
Genetic Background: involves: 129S2/SvPas

 MP:0001473 reduced long term potentiation "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3]
Show

Allelic Composition: Ccne2tm1Pisc/Ccne2tm1Pisc
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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