ENSMUSG00000050315


Mus musculus

Features
Gene ID: ENSMUSG00000050315
  
Biological name :Synpo2
  
Synonyms : Q91YE8 / Synaptopodin-2 / Synpo2
  
Possible biological names infered from orthology : Q9UMS6
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: G1
Gene start: 123076519
Gene end: 123236149
  
Corresponding Affymetrix probe sets: 10501903 (MoGene1.0st)   1435399_at (Mouse Genome 430 2.0 Array)   1441206_at (Mouse Genome 430 2.0 Array)   1450828_at (Mouse Genome 430 2.0 Array)   1452879_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000102035
Ensembl peptide - ENSMUSP00000142508
Ensembl peptide - ENSMUSP00000142426
Ensembl peptide - ENSMUSP00000123396
Ensembl peptide - ENSMUSP00000051570
Ensembl peptide - ENSMUSP00000102034
NCBI entrez gene - 118449     See in Manteia.
MGI - MGI:2153070
RefSeq - XM_006500925
RefSeq - NM_080451
RefSeq Peptide - NP_536699
swissprot - F6WWS1
swissprot - D3YVV9
swissprot - E9Q1U2
swissprot - Q91YE8
swissprot - A0A0G2JDM5
Ensembl - ENSMUSG00000050315
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 synpo2bENSDARG00000077157Danio rerio
 SYNPO2ENSGALG00000011994Gallus gallus
 Q9UMS6ENSG00000172403Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BWB1 / Synpo2l / synaptopodin 2-like / Q9H987*ENSMUSG0000003937623
Synpo / Q8CC35 / Synaptopodin / Q8N3V7*ENSMUSG0000004307916


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IEA
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0032233 positive regulation of actin filament bundle assembly IBA
 biological_processGO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity ISO
 cellular_componentGO:0001725 stress fiber ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0015629 actin cytoskeleton IBA
 cellular_componentGO:0030018 Z disc IBA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0099023 tethering complex IEA
 molecular_functionGO:0003779 actin binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031005 filamin binding ISO
 molecular_functionGO:0051371 muscle alpha-actinin binding IDA
 molecular_functionGO:0051393 alpha-actinin binding ISO
 molecular_functionGO:0071889 14-3-3 protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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