ENSMUSG00000046049


Mus musculus

Features
Gene ID: ENSMUSG00000046049
  
Biological name :Rp1l1
  
Synonyms : Q8CGM2 / retinitis pigmentosa 1 homolog like 1 / Rp1l1
  
Possible biological names infered from orthology : RP1 like 1
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D1
Gene start: 63992506
Gene end: 64035025
  
Corresponding Affymetrix probe sets: 10415890 (MoGene1.0st)   1457622_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055449
NCBI entrez gene - 271209     See in Manteia.
MGI - MGI:2384303
RefSeq - NM_146246
RefSeq Peptide - NP_666358
swissprot - A1L340
swissprot - Q8CGM2
Ensembl - ENSMUSG00000046049
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rp1l1aENSDARG00000089458Danio rerio
 rp1l1bENSDARG00000088377Danio rerio
 ENSGALG00000028138Gallus gallus
 RP1L1ENSG00000183638Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rp1 / P56716 / Oxygen-regulated protein 1 / P56715* / RP1, axonemal microtubule associated*ENSMUSG0000002590015
Dcdc2a / Q5DU00 / Doublecortin domain-containing protein 2 / DCDC2* / Q9UHG0* / doublecortin domain containing 2*ENSMUSG000000359105
Dcdc2b / doublecortin domain containing 2B / A2VCK2*ENSMUSG000000785524
Dcdc2c / Q9D1B8 / Doublecortin domain-containing protein 2C / A8MYV0* / doublecortin domain containing 2C*ENSMUSG000000206332


Protein motifs (from Interpro)
Interpro ID Name
 IPR003533  Doublecortin domain
 IPR036572  Doublecortin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0035082 axoneme assembly IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042461 photoreceptor cell development IMP
 biological_processGO:0045494 photoreceptor cell maintenance IMP
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0060041 retina development in camera-type eye IBA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005930 axoneme IDA
 cellular_componentGO:0032391 photoreceptor connecting cilium IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001327 reduced retinal photoreceptor cell number "fewer than the expected number of rods and/or cones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0003729 abnormal photoreceptor outer segments "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Rp1tm1Jnz/Rp1+,Rp1l1tm1Jnz/Rp1l1+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Rp1tm1Jnz/Rp1+,Rp1l1tm1Jnz/Rp1l1+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0008451 retinal rod cell degeneration "a retrogressive impairment of function or destruction of one of the photoreceptor cell types of the vertebrate retina, in which the photopigment is in stacks of membranous disks separate from the outer cell membrane" [MESH:A08.663.650.650.670.650]
Show

Allelic Composition: Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0008587 short photoreceptor outer segment "decreased length of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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