ENSMUSG00000035910


Mus musculus

Features
Gene ID: ENSMUSG00000035910
  
Biological name :Dcdc2a
  
Synonyms : Dcdc2a / Doublecortin domain-containing protein 2 / Q5DU00
  
Possible biological names infered from orthology : DCDC2 / doublecortin domain containing 2 / Q9UHG0
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.1
Gene start: 25056004
Gene end: 25210706
  
Corresponding Affymetrix probe sets: 10404250 (MoGene1.0st)   1441503_at (Mouse Genome 430 2.0 Array)   1459661_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047641
Ensembl peptide - ENSMUSP00000063650
NCBI entrez gene - 195208     See in Manteia.
MGI - MGI:2652818
RefSeq - XM_011244294
RefSeq - NM_001195617
RefSeq - NM_177577
RefSeq - XM_006516604
RefSeq - XM_011244291
RefSeq - XM_011244292
RefSeq Peptide - NP_001182546
RefSeq Peptide - NP_808245
swissprot - Q5DU00
swissprot - R4GML1
Ensembl - ENSMUSG00000035910
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DCDC2ENSGALG00000042454Gallus gallus
 DCDC2ENSG00000146038Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dcdc2b / doublecortin domain containing 2B / A2VCK2*ENSMUSG0000007855223
Rp1 / P56716 / Oxygen-regulated protein 1 / P56715* / RP1, axonemal microtubule associated*ENSMUSG0000002590020
Rp1l1 / Q8CGM2 / retinitis pigmentosa 1 homolog like 1 / RP1 like 1*ENSMUSG0000004604918
Dcdc2c / Q9D1B8 / Doublecortin domain-containing protein 2C / A8MYV0* / doublecortin domain containing 2C*ENSMUSG0000002063311


Protein motifs (from Interpro)
Interpro ID Name
 IPR003533  Doublecortin domain
 IPR033036  Doublecortin domain-containing protein 2
 IPR036572  Doublecortin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008542 visual learning IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0045880 positive regulation of smoothened signaling pathway IEA
 biological_processGO:0048813 dendrite morphogenesis IGI
 biological_processGO:0060271 cilium assembly IEA
 biological_processGO:1902017 regulation of cilium assembly IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005930 axoneme IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0060091 kinocilium IEA
 cellular_componentGO:0072686 mitotic spindle IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0019894 kinesin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Grntm1.1Geno/Grntm1.1Geno
Genetic Background: involves: 129 * C57BL/6J

 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Grntm1.1Geno/Grntm1.1Geno
Genetic Background: involves: 129 * C57BL/6J

 MP:0002800 abnormal short-term recognition memory "defects in the short-term memory for objects is established during the first few minutes after training" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Grntm1.1Geno/Grntm1.1Geno
Genetic Background: involves: 129 * C57BL/6J

 MP:0008428 abnormal spatial working memory "anomaly in the ability to spontaneously process spatial location information in order to naviagate or perform other behavior using such locational cues, without previous encounters or training at that location" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grntm1.1Geno/Grntm1.1Geno
Genetic Background: involves: 129 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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