ENSMUSG00000047879


Mus musculus

Features
Gene ID: ENSMUSG00000047879
  
Biological name :Usp14
  
Synonyms : Q9JMA1 / ubiquitin specific peptidase 14 / Usp14
  
Possible biological names infered from orthology : P54578
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: A1
Gene start: 9995432
Gene end: 10045119
  
Corresponding Affymetrix probe sets: 10457409 (MoGene1.0st)   1416208_at (Mouse Genome 430 2.0 Array)   1437714_x_at (Mouse Genome 430 2.0 Array)   1439201_at (Mouse Genome 430 2.0 Array)   1455829_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000089728
Ensembl peptide - ENSMUSP00000112368
NCBI entrez gene - 59025     See in Manteia.
MGI - MGI:1928898
RefSeq - XM_017317959
RefSeq - NM_001038589
RefSeq - NM_021522
RefSeq - XM_006526134
RefSeq Peptide - NP_067497
RefSeq Peptide - NP_001033678
swissprot - Q9JMA1
swissprot - E9PYI8
Ensembl - ENSMUSG00000047879
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp14ENSDARG00000025889Danio rerio
 USP14ENSGALG00000014920Gallus gallus
 USP14ENSG00000101557Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR019954  Ubiquitin conserved site
 IPR028889  Ubiquitin specific protease domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007268 chemical synaptic transmission IMP
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050920 regulation of chemotaxis IEA
 biological_processGO:0061136 regulation of proteasomal protein catabolic process IEA
 biological_processGO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process IEA
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IDA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0004866 endopeptidase inhibitor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0070628 proteasome binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000743 muscle spasms "muscular twitching, cramps and seizures ; frequently associated with calcium deficiency, hypoparathyroidism, vitamin D deficiency or alkalosis " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: B6;CByJ-Usp14nmf375/J

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

Allelic Composition: Nxf1Mvb1/Nxf1Mvb1,Usp14ax-J/Usp14ax-J
Genetic Background: involves: C57BL/6

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

 MP:0000749 muscle degeneration "pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: B6;CByJ-Usp14nmf375/J

 MP:0000753 paralysis "loss of power of voluntary movement in a muscle through injury or disease of its nerve supply" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000781 reduced size of corpus callosum "smaller commissural plate interconnecting the cortical hemispheres of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000812 abnormal dentate gyrus morphology "absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000841 abnormal hindbrain morphology "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000848 abnormal pons "malformed band of nerve fibers in the brain connecting the medulla oblongata and the mesencephalon; this region conveys information about movement from the cerebral hemisphere to the cerebellum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:1776, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000876 Purkinje cell degeneration "a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [J:46854]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000955 abnormal spinal cord morphology "malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: B6;CByJ-Usp14nmf375/J

 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
Show

Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

Allelic Composition: Usp14ax-J/Usp14ax-J
Genetic Background: B6.Cg-Usp14ax-J

 MP:0001077 abnormal spinal nerve morphology "any anomaly, deformity, or malformation of the any of the 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

Allelic Composition: Usp14ax-J/Usp14ax-J
Genetic Background: B6.Cg-Usp14ax-J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: B6;CByJ-Usp14nmf375/J

Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

 MP:0001473 reduced long term potentiation "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: B6;CByJ-Usp14nmf375/J

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0001900 impaired synaptic plasticity "decreased or inability of the nervous system to change its reactivity as a result of successive activations " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

Allelic Composition: Usp14ax-J/Usp14ax-J
Genetic Background: B6.Cg-Usp14ax-J

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002199 abnormal brain commissure morphology "absent or defective structure in a bundle of nerve fibers connecting the two brain hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002269 muscular atrophy "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002734 abnormal mechanical nociception "abnormal capability to sense pain elicited by mechanical stimulation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

 MP:0002916 increased synaptic depression "increase in the duration of the reduction of effectiveness of synaptic connections between neurons and target after repetitive stimulation" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002920 reduced paired-pulse facilitation "decrease in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of increase of neurotransmitter release at the second stimulus" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002922 decreased post-tetanic potential "reduction in the size or duration of potentials that persist after tetanic stimulation of central synapses" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003049 abnormal lumbar vertebrae morphology "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0003203 increased neuron apoptosis "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003225 axonal dystrophy "axon degeneration resulting from inadequate or faulty metabolism" [RGD:Rat Genome Database submission]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: B6;CByJ-Usp14nmf375/J

 MP:0003415 priapism "prolonged penile erection, often painful and without sexual desire " [smb:Susan M Bello, Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0003633 abnormal nervous system physiology 
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

 MP:0003635 abnormal synaptic transmission "defect in the communication from a neuron to a target across a synapse " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0004098 abnormal granule neuron "any structural anomaly of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0004166 abnormal limbic system morphology "any malformation or absence of any of a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory; these structures act together to control the endocrine system and the autonomic nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0004708 short lumbar vertebrae "reduced length of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0004835 abnormal miniature endplate potential "defect in the size or duration of spontaneous currents detected in PNS postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005277 abnormal brainstem morphology "anomalous structure of the midbrain, pons, or medulla" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:82670]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: B6;CByJ-Usp14nmf375/J

 MP:0005445 abnormal neurotransmitter release "aberration in the secretion of endogenous signaling molecules normally secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008027 abnormal spinal cord white matter morphology "any structural anomaly of the regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0008222 decreased hippocampal commissure size "reduced size of the triangular subcallosal plate of commissural fibers resulting from the converging of the right and left fornix bundles which exchange numerous fibers and which curve back in the contralateral fornix to end in the hippocampus of the opposite side" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0008232 abnormal cingulum morphology "any structural anomaly of the white matter fiber bundle that projects from the cingulate gyrus to the entorhinal cortex in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0008283 small hippocampus "reduced size of the deep lying structure of the cerebrum involved with memory storage and spatial navigation" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0009434 paraparesis "a weakness affecting lower limbs" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: B6;CByJ-Usp14nmf375/J

 MP:0009940 abnormal hippocampus pyramidal cell morphology "any structural anomaly of the projection neuron in the pyramidal layer of the hippocampus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Usp14nmf375/Usp14nmf375
Genetic Background: C.B6-Usp14nmf375

Allelic Composition: Usp14ax-J/Usp14ax-J
Genetic Background: C.Cg-Usp14ax-J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Txniptm1b(EUCOMM)Hmgu/Txniptm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Txniptm1b(EUCOMM)Hmgu/H

 MP:0012089 decreased midbrain size "size reduction or truncation of the brain region derived from the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions in the adult, including eye movement and coordination of auditory and visual reflexes" [MGI:anna, MGI:csmith]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0020560 abnormal pontine nuclei morphology "any structural anomaly of nuclei in the basal pons, intermingled among the descending axons from the cortex, that receive neocortcial input and give rise to many axons that cross the midline to enter the contralateral cerebellum" [UBERON:0002151]
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Allelic Composition: Adrb3tm1Jpg/Adrb3tm1Jpg
Genetic Background: involves: 129S4/SvJae * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039041 Adrm1 / Q9JKV1 / Proteasomal ubiquitin receptor ADRM1 / Q16186* / adhesion regulating molecule 1*  / reaction / complex






 

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