ENSMUSG00000048027


Mus musculus

Features
Gene ID: ENSMUSG00000048027
  
Biological name :Rgmb
  
Synonyms : Q7TQ33 / Rgmb / RGM domain family member B
  
Possible biological names infered from orthology : Q6NW40 / repulsive guidance molecule BMP co-receptor b
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A2
Gene start: 15806253
Gene end: 15826586
  
Corresponding Affymetrix probe sets: 10448081 (MoGene1.0st)   1428429_at (Mouse Genome 430 2.0 Array)   1428430_at (Mouse Genome 430 2.0 Array)   1433586_at (Mouse Genome 430 2.0 Array)   1433587_at (Mouse Genome 430 2.0 Array)   1442811_at (Mouse Genome 430 2.0 Array)   1459366_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126177
NCBI entrez gene - 68799     See in Manteia.
MGI - MGI:1916049
RefSeq - XM_006524865
RefSeq - NM_178615
RefSeq - XM_006524863
RefSeq - XM_006524864
RefSeq Peptide - NP_848730
swissprot - Q7TQ33
Ensembl - ENSMUSG00000048027
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgmbENSDARG00000079323Danio rerio
 RGMBENSGALG00000015284Gallus gallus
 RGMBENSG00000174136Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rgma / Q6PCX7 / Repulsive guidance molecule A / Q96B86* / repulsive guidance molecule BMP co-receptor a*ENSMUSG0000007050947
Hfe2 / Q7TQ32 / Hemojuvelin / Q6ZVN8* / hemochromatosis type 2 (juvenile)*ENSMUSG0000003840340


Protein motifs (from Interpro)
Interpro ID Name
 IPR009496  Repulsive guidance molecule, C-terminal
 IPR010536  Repulsive guidance molecule, N-terminal
 IPR016123  Mog1/PsbP, alpha/beta/alpha sandwich
 IPR033608  RGM domain family member B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IDA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0030509 BMP signaling pathway IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0046658 anchored component of plasma membrane IDA
 molecular_functionGO:0015026 coreceptor activity IBA
 molecular_functionGO:0042802 identical protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Runx1tm3Itan/Runx1tm3Itan
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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