ENSMUSG00000048371


Mus musculus

Features
Gene ID: ENSMUSG00000048371
  
Biological name :Pdp2
  
Synonyms : Pdp2 / pyruvate dehyrogenase phosphatase catalytic subunit 2
  
Possible biological names infered from orthology : Q9P2J9
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: D3
Gene start: 104591451
Gene end: 104599026
  
Corresponding Affymetrix probe sets: 10574488 (MoGene1.0st)   1428996_at (Mouse Genome 430 2.0 Array)   1441285_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092821
NCBI entrez gene - 382051     See in Manteia.
MGI - MGI:1918878
RefSeq - NM_001024606
RefSeq - XM_006531160
RefSeq Peptide - NP_001019777
swissprot - Q504M2
Ensembl - ENSMUSG00000048371
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdp2ENSDARG00000058571Danio rerio
 PDP2ENSGALG00000005146Gallus gallus
 PDP2ENSG00000172840Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pdp1 / Q3UV70 / pyruvate dehyrogenase phosphatase catalytic subunit 1 / Q9P0J1*ENSMUSG0000004922548


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family
 IPR036457  PPM-type phosphatase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000033624 Pdpr / Q7TSQ8 / Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial / Q8NCN5* / pyruvate dehydrogenase phosphatase regulatory subunit*  / complex






 

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contact: otassy@igbmc.fr