ENSMUSG00000033624


Mus musculus

Features
Gene ID: ENSMUSG00000033624
  
Biological name :Pdpr
  
Synonyms : Pdpr / Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial / Q7TSQ8
  
Possible biological names infered from orthology : pyruvate dehydrogenase phosphatase regulatory subunit / Q8NCN5
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 111094630
Gene end: 111137074
  
Corresponding Affymetrix probe sets: 10575578 (MoGene1.0st)   1434480_at (Mouse Genome 430 2.0 Array)   1444665_at (Mouse Genome 430 2.0 Array)   1454980_at (Mouse Genome 430 2.0 Array)   1459869_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117570
Ensembl peptide - ENSMUSP00000121325
Ensembl peptide - ENSMUSP00000046639
NCBI entrez gene - 319518     See in Manteia.
MGI - MGI:2442188
RefSeq - XM_006531084
RefSeq - XM_017312852
RefSeq - NM_198308
RefSeq Peptide - NP_938050
swissprot - Q7TSQ8
swissprot - D6RD07
swissprot - D3Z443
Ensembl - ENSMUSG00000033624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDPRENSDARG00000103288Danio rerio
 PDPRENSGALG00000002690Gallus gallus
 PDPRENSG00000090857Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sardh / Q99LB7 / sarcosine dehydrogenase / Q9UL12*ENSMUSG0000000961432
Dmgdh / Q9DBT9 / Dimethylglycine dehydrogenase, mitochondrial / Q9UI17* / dimethylglycine dehydrogenase*ENSMUSG0000004210230
Amt / Q8CFA2 / Aminomethyltransferase, mitochondrial / P48728* / aminomethyltransferase*ENSMUSG0000003260710


Protein motifs (from Interpro)
Interpro ID Name
 IPR006076  FAD dependent oxidoreductase
 IPR006222  Aminomethyltransferase, folate-binding domain
 IPR013977  Glycine cleavage T-protein, C-terminal barrel domain
 IPR029043  Glycine cleavage T-protein/YgfZ, C-terminal
 IPR032503  FAD dependent oxidoreductase, central domain
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix IBA
 molecular_functionGO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000048371 Pdp2 / pyruvate dehyrogenase phosphatase catalytic subunit 2 / Q9P2J9*  / complex
 ENSMUSG00000049225 Pdp1 / Q3UV70 / pyruvate dehyrogenase phosphatase catalytic subunit 1 / Q9P0J1*  / complex






 

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