ENSMUSG00000048578


Mus musculus

Features
Gene ID: ENSMUSG00000048578
  
Biological name :Mlec
  
Synonyms : Malectin / Mlec / Q6ZQI3
  
Possible biological names infered from orthology : Q14165
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 115142981
Gene end: 115158179
  
Corresponding Affymetrix probe sets: 10532944 (MoGene1.0st)   10532954 (MoGene1.0st)   1436508_at (Mouse Genome 430 2.0 Array)   1436509_at (Mouse Genome 430 2.0 Array)   1448569_at (Mouse Genome 430 2.0 Array)   1458652_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107749
NCBI entrez gene - 109154     See in Manteia.
MGI - MGI:1924015
RefSeq - NM_175403
RefSeq Peptide - NP_780612
swissprot - Q6ZQI3
Ensembl - ENSMUSG00000048578
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mlecENSDARG00000059630Danio rerio
 MLECENSGALG00000007102Gallus gallus
 MLECENSG00000110917Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021720  Malectin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030246 carbohydrate binding ISS


Pathways (from Reactome)
Pathway description
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
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Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0010850 increased effector memory CD8-positive, alpha-beta T cell number "increased number of CD8-positive, alpha beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000913, GO_REF:0000031, GOC:add, GOC:pam, PMID:20146720]
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Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003402 O08795 / Prkcsh / protein kinase C substrate 80K-H / P14314*  / reaction
 ENSMUSG00000071650 Ganab / Q8BHN3 / Neutral alpha-glucosidase AB / Q14697* / glucosidase II alpha subunit*  / reaction






 

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