ENSMUSG00000071650


Mus musculus

Features
Gene ID: ENSMUSG00000071650
  
Biological name :Ganab
  
Synonyms : Ganab / Neutral alpha-glucosidase AB / Q8BHN3
  
Possible biological names infered from orthology : glucosidase II alpha subunit / Q14697
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 8898090
Gene end: 8916663
  
Corresponding Affymetrix probe sets: 10461277 (MoGene1.0st)   1415787_at (Mouse Genome 430 2.0 Array)   1437812_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000093965
NCBI entrez gene - 14376     See in Manteia.
MGI - MGI:1097667
RefSeq - XM_006526678
RefSeq - NM_001293621
RefSeq - NM_008060
RefSeq - XM_006526677
RefSeq Peptide - NP_032086
RefSeq Peptide - NP_001280550
swissprot - Q8BHN3
swissprot - A1A4T2
Ensembl - ENSMUSG00000071650
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ganabENSDARG00000076811Danio rerio
 zgc:171967ENSDARG00000076888Danio rerio
 GANABENSG00000089597Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ganc / glucosidase alpha, neutral C / Q8TET4*ENSMUSG0000006264649
Gaa / P70699 / Lysosomal alpha-glucosidase / P10253* / glucosidase alpha, acid*ENSMUSG0000002557926
Mgam / maltase-glucoamylase / O43451*ENSMUSG0000006858724
Sis / sucrase-isomaltase / SI* / P14410*ENSMUSG0000002779022
Q69ZQ1 / AI464131 / Myosis-regulating glycosidase / MYORG* / Q6NSJ0* / myogenesis regulating glycosidase (putative)*ENSMUSG0000004631212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000322  Glycoside hydrolase family 31
 IPR011013  Galactose mutarotase-like domain superfamily
 IPR017853  Glycoside hydrolase superfamily
 IPR025887  Glycoside hydrolase family 31, N-terminal domain
 IPR030458  Glycosyl hydrolases family 31, active site
 IPR030459  Glycosyl hydrolases family 31, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006491 N-glycan processing TAS
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0017177 glucosidase II complex IPI
 cellular_componentGO:0031012 extracellular matrix ISO
 cellular_componentGO:0042470 melanosome IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015926 glucosidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0033919 glucan 1,3-alpha-glucosidase activity IEA


Pathways (from Reactome)
Pathway description
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Calnexin/calreticulin cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003402 O08795 / Prkcsh / protein kinase C substrate 80K-H / P14314*  / complex
 ENSMUSG00000020368 Canx / P35564 / Calnexin / P27824*  / reaction
 ENSMUSG00000027248 Pdia3 / P27773 / Protein disulfide-isomerase A3 / P30101* / protein disulfide isomerase family A member 3*  / reaction
 ENSMUSG00000003814 Calr / P14211 / Calreticulin / P27797*  / reaction
 ENSMUSG00000048578 Mlec / Q6ZQI3 / Malectin / Q14165*  / reaction






 

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