ENSMUSG00000049295


Mus musculus

Features
Gene ID: ENSMUSG00000049295
  
Biological name :Zfp219
  
Synonyms : Q6IQX8 / Zfp219 / zinc finger protein 219
  
Possible biological names infered from orthology : Q9P2Y4 / ZNF219
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C2
Gene start: 52006077
Gene end: 52020733
  
Corresponding Affymetrix probe sets: 10419596 (MoGene1.0st)   1424301_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068184
Ensembl peptide - ENSMUSP00000126854
Ensembl peptide - ENSMUSP00000153742
Ensembl peptide - ENSMUSP00000153966
Ensembl peptide - ENSMUSP00000154709
Ensembl peptide - ENSMUSP00000154768
Ensembl peptide - ENSMUSP00000154096
Ensembl peptide - ENSMUSP00000154200
Ensembl peptide - ENSMUSP00000154367
Ensembl peptide - ENSMUSP00000154448
Ensembl peptide - ENSMUSP00000154698
NCBI entrez gene - 69890     See in Manteia.
MGI - MGI:1917140
RefSeq - XM_017316180
RefSeq - NM_001253694
RefSeq - NM_001253695
RefSeq - NM_001253696
RefSeq - NM_027248
RefSeq - XM_006519503
RefSeq - XM_006519504
RefSeq - XM_006519505
RefSeq - XM_006519506
RefSeq - XM_011245176
RefSeq - XM_011245177
RefSeq - XM_006519498
RefSeq - XM_006519499
RefSeq - XM_006519501
RefSeq - XM_006519502
RefSeq Peptide - NP_001240624
RefSeq Peptide - NP_001240625
RefSeq Peptide - NP_081524
RefSeq Peptide - NP_001240623
swissprot - Q4VA98
swissprot - Q6IQX8
Ensembl - ENSMUSG00000049295
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1QQA8ENSDARG00000079738Danio rerio
 Q9P2Y4ENSG00000165804Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8K083 / Zfp536 / zinc finger protein 536 / O15090* / ZNF536*ENSMUSG0000004345639
Q7TSH3 / Zfp516 / zinc finger protein 516 / Q92618* / ZNF516*ENSMUSG0000005888122
Zfp217 / zinc finger protein 217 / O75362* / ZNF217*ENSMUSG0000005205620


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated ISO
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0006366 transcription by RNA polymerase II IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0060174 limb bud formation IEP
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000947 convulsive seizures "seizures characterized by uncontrolled motor activity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Smarcd2tm1.1(KOMP)Vlcg/Smarcd2+
Genetic Background: C57BL/6N-Smarcd2tm1.1(KOMP)Vlcg/Ucd

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Smarcd2tm1.1(KOMP)Vlcg/Smarcd2+
Genetic Background: C57BL/6N-Smarcd2tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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