ENSMUSG00000049922


Mus musculus

Features
Gene ID: ENSMUSG00000049922
  
Biological name :Slc35c1
  
Synonyms : Q8BLX4 / Slc35c1 / solute carrier family 35, member C1
  
Possible biological names infered from orthology : Q96A29
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E1
Gene start: 92452764
Gene end: 92460538
  
Corresponding Affymetrix probe sets: 10485183 (MoGene1.0st)   1452139_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000063461
Ensembl peptide - ENSMUSP00000119271
Ensembl peptide - ENSMUSP00000137748
NCBI entrez gene - 228368     See in Manteia.
MGI - MGI:2443301
RefSeq - NM_145832
RefSeq - NM_211358
RefSeq Peptide - NP_665831
RefSeq Peptide - NP_997597
swissprot - Q8R2I1
swissprot - Q78H73
swissprot - Q8BLX4
swissprot - M0QWB9
Ensembl - ENSMUSG00000049922
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc35c1ENSDARG00000104669Danio rerio
 SLC35C1ENSGALG00000008438Gallus gallus
 Q96A29ENSG00000181830Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004853  Sugar phosphate transporter domain
 IPR029666  GDP-fucose transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008643 carbohydrate transport IEA
 biological_processGO:0030259 lipid glycosylation IMP
 biological_processGO:0036085 GDP-fucose import into Golgi lumen IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005457 GDP-fucose transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
GDP-fucose biosynthesis
Transport of nucleotide sugars


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000218 increased WBC count "greater than normal WBC numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0000420 ruffled hair "fuzzy, irregular appearance of the hair" [J:50844]
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Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001183 overexpanded alveoli "expanded volume of the saclike terminal dilation of the respiratory bronchioles" [J:66345]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001386 abnormal maternal nurturing "failure of mothers to tend offspring" [J:39801]
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Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001504 abnormal posture "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
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Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0002345 abnormal lymph node primary follicle "anomaly in the immunologically inactive B cell area of the lymph node cortex" [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0003628 abnormal lymphocyte adhesion "anomaly in the number of or process by which lymphocytes adhere to the luminal aspects of high endothelial venules prior to transmigration out of the vessel" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95656]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0005011 increased eosinophil count "greater than normal eosinophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0005013 increased lymphocyte number "greater than normal white blood cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0005266 abnormal metabolism "anomalous chemical and physical changes occurring in tissue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0008101 lymph node hypoplasia "underdevelopment or reduced size, usually due to a reduced cell number, in the lymph nodes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0010903 abnormal pulmonary alveolus wall morphology 
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Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011084 partial lethality at weaning "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms at weaning age" [MGI:csmith]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Slc35c1tm1Cknr/Slc35c1tm1Cknr
Genetic Background: involves: 129P2/OlaHsd * 129/Sv

 MP:0020332 impaired leukocyte tethering or rolling "reduced ability or inability in the transient adhesive interactions between leukocytes and endothelial cells lining blood vessels mediated primarily by selectins and which are typically the first step in cellular extravasation" [GO:0050901, ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Abca3tm1Nina/Abca3tm1Nina
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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