ENSMUSG00000050447


Mus musculus

Features
Gene ID: ENSMUSG00000050447
  
Biological name :Lypd6
  
Synonyms : Ly6/PLAUR domain-containing protein 6 / Lypd6 / Q8BPP5
  
Possible biological names infered from orthology : LY6/PLAUR domain containing 6 / Q86Y78
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C1.1
Gene start: 50066429
Gene end: 50193569
  
Corresponding Affymetrix probe sets: 10472034 (MoGene1.0st)   1454969_at (Mouse Genome 430 2.0 Array)   1456138_at (Mouse Genome 430 2.0 Array)   1457843_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116803
Ensembl peptide - ENSMUSP00000131002
Ensembl peptide - ENSMUSP00000119755
Ensembl peptide - ENSMUSP00000061578
Ensembl peptide - ENSMUSP00000108332
NCBI entrez gene - 320343     See in Manteia.
MGI - MGI:2443848
RefSeq - NM_177139
RefSeq - XM_011239116
RefSeq Peptide - NP_796113
swissprot - A2AQT4
swissprot - Q8BPP5
swissprot - A2AQT3
Ensembl - ENSMUSG00000050447
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lypd6ENSDARG00000004307Danio rerio
 LYPD6ENSGALG00000012470Gallus gallus
 LYPD6ENSG00000187123Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lypd6b / Q9D7F2 / Ly6/PLAUR domain-containing protein 6B / Q8NI32* / LY6/PLAUR domain containing 6B*ENSMUSG0000002676538


Protein motifs (from Interpro)
Interpro ID Name
 IPR031574  Ly6/PLAUR domain-containing protein 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0099601 regulation of neurotransmitter receptor activity IEA
 biological_processGO:2000272 negative regulation of signaling receptor activity IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0030548 acetylcholine receptor regulator activity IMP
 molecular_functionGO:0030550 acetylcholine receptor inhibitor activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Leprtm1b(EUCOMM)Wtsi/Leprtm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Leprtm1b(EUCOMM)Wtsi/H

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
Show

Allelic Composition: Leprtm1b(EUCOMM)Wtsi/Leprtm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Leprtm1b(EUCOMM)Wtsi/H

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Leprtm1b(EUCOMM)Wtsi/Leprtm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Leprtm1b(EUCOMM)Wtsi/H

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Leprtm1b(EUCOMM)Wtsi/Leprtm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Leprtm1b(EUCOMM)Wtsi/H

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT2)Thl/0,Picalmtm1.1Tmae/Picalmtm1.1Tmae
Genetic Background: involves: 129 * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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