ENSMUSG00000051043


Mus musculus

Features
Gene ID: ENSMUSG00000051043
  
Biological name :Gprc5c
  
Synonyms : Gprc5c / G protein-coupled receptor, family C, group 5, member C
  
Possible biological names infered from orthology : G protein-coupled receptor class C group 5 member C / Q9NQ84
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 114851152
Gene end: 114872617
  
Corresponding Affymetrix probe sets: 10382425 (MoGene1.0st)   10382435 (MoGene1.0st)   1424450_at (Mouse Genome 430 2.0 Array)   1452947_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116786
Ensembl peptide - ENSMUSP00000114335
Ensembl peptide - ENSMUSP00000118667
Ensembl peptide - ENSMUSP00000136702
Ensembl peptide - ENSMUSP00000121572
Ensembl peptide - ENSMUSP00000121524
Ensembl peptide - ENSMUSP00000021071
Ensembl peptide - ENSMUSP00000061760
NCBI entrez gene - 70355     See in Manteia.
MGI - MGI:1917605
RefSeq - XM_006534165
RefSeq - NM_001110337
RefSeq - NM_001110338
RefSeq - NM_147217
RefSeq - XM_006534161
RefSeq - XM_006534162
RefSeq - XM_006534163
RefSeq - XM_006534164
RefSeq Peptide - NP_671750
RefSeq Peptide - NP_001103807
RefSeq Peptide - NP_001103808
swissprot - E9PZP1
swissprot - B7FAU0
swissprot - B7FAT9
swissprot - I7HPW4
swissprot - J3JS84
swissprot - B7FAT7
swissprot - B7FAT8
Ensembl - ENSMUSG00000051043
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gprc5cENSDARG00000100862Danio rerio
 GPRC5CENSGALG00000021362Gallus gallus
 GPRC5CENSG00000170412Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gprc5b / Q923Z0 / G protein-coupled receptor, family C, group 5, member B / Q9NZH0* / G protein-coupled receptor class C group 5 member B*ENSMUSG0000000873436
Gprc5a / G protein-coupled receptor class C group 5 member A / Q8NFJ5*ENSMUSG0000004673331
Gprc5d / Q9JIL6 / G protein-coupled receptor, family C, group 5, member D / Q9NZD1* / G protein-coupled receptor class C group 5 member D*ENSMUSG0000003020527


Protein motifs (from Interpro)
Interpro ID Name
 IPR017978  GPCR family 3, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Prkab2tm1Grst/Prkab2tm1Grst,Tg(Ckmm-cre)5Khn/0
Genetic Background: involves: C57BL/6 * FVB

 MP:0002606 increased basophil count "higher than average number of basophils as measured by the percent of the total number of leukocytes" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, MPD:Mouse Phenome Database]
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Allelic Composition: Prkab2tm1Grst/Prkab2tm1Grst,Tg(Ckmm-cre)5Khn/0
Genetic Background: involves: C57BL/6 * FVB

 MP:0002640 reticulocytosis "an increase in the number of reticulocytes in the blood" [J:78271, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
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Allelic Composition: Prkab2tm1Grst/Prkab2tm1Grst,Tg(Ckmm-cre)5Khn/0
Genetic Background: involves: C57BL/6 * FVB

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Prkab2tm1Grst/Prkab2tm1Grst,Tg(Ckmm-cre)5Khn/0
Genetic Background: involves: C57BL/6 * FVB

 MP:0005642 decreased mean corpuscular hemoglobin concentration "less than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
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Allelic Composition: Prkab2tm1Grst/Prkab2tm1Grst,Tg(Ckmm-cre)5Khn/0
Genetic Background: involves: C57BL/6 * FVB

 MP:0011971 increased circulating lactate dehydrogenase level "elevated blood level of the tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of lactate and pyruvate; measurements of circulating levels are used clinically as a diagnostic indicator of tissue breakdown, some forms of cancer or particular infection types" [MeSH:D08.811.682.047.551.400, MGI:csmith]
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Allelic Composition: Prkab2tm1Grst/Prkab2tm1Grst,Tg(Ckmm-cre)5Khn/0
Genetic Background: involves: C57BL/6 * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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